C Kahana
Overview
Explore the profile of C Kahana including associated specialties, affiliations and a list of published articles.
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Articles
41
Citations
1175
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Recent Articles
1.
German L, Kahana C, Rosenfeld V, Zabrowsky I, Wiezer Z, Fraser D, et al.
J Nutr Health Aging
. 2011 Jan;
15(1):3-8.
PMID: 21267514
Unlabelled: Depression is associated with nutritional deterioration in older persons and is highly prevalent among people of low socioeconomic status (LSES). Objectives: To determine the prevalence of depressive symptoms and...
2.
Kahana C
Amino Acids
. 2007 Apr;
33(2):225-30.
PMID: 17404802
Protein degradation mediated by the ubiquitin/proteasome system is the major route for the degradation of cellular proteins. In this pathway the ubiquitination of the target proteins is manifested via the...
3.
Keren-Paz A, Bercovich Z, Kahana C
Biochem Soc Trans
. 2007 Mar;
35(Pt 2):311-3.
PMID: 17371267
ODC (ornithine decarboxylase) is a central regulator of cellular polyamine synthesis. ODC is a highly regulated enzyme stimulated by a variety of growth-promoting stimuli. ODC overexpression leads to cellular transformation....
4.
Keren-Paz A, Bercovich Z, Porat Z, Erez O, Brener O, Kahana C
Oncogene
. 2006 Mar;
25(37):5163-72.
PMID: 16568078
Antizyme inhibitor (AzI) is a homolog of ornithine decarboxylase (ODC), a key enzyme of polyamine synthesis. Antizyme inhibitor retains no enzymatic activity, but exhibits high affinity to antizyme (Az), a...
5.
Porat Z, Wender N, Erez O, Kahana C
Cell Mol Life Sci
. 2005 Dec;
62(24):3106-16.
PMID: 16374585
Polyamines are small charged molecules essential for various cellular functions, but at high levels they are cytotoxic. Two yeast kinases, SKY1 and PTK2, have been demonstrated to regulate polyamine tolerance....
6.
Ciechanover A, Gonen H, Bercovich B, Cohen S, Fajerman I, Israel A, et al.
Biochimie
. 2001 Apr;
83(3-4):341-9.
PMID: 11295495
In most cases, target proteins of the ubiquitin system are completely degraded. In several exceptions, such as the first step in the activation of the transcriptional regulator NF-kappaB, the substrate,...
7.
Erez O, Kahana C
Mol Cell Biol
. 2000 Dec;
21(1):175-84.
PMID: 11113192
Although most cells are capable of transporting polyamines, the mechanism that regulates polyamine transport in eukaryotes is still largely unknown. Using a genetic screen for clones capable of restoring spermine...
8.
Goldstaub D, Gradi A, Bercovitch Z, Grosmann Z, Nophar Y, Luria S, et al.
Mol Cell Biol
. 2000 Jan;
20(4):1271-7.
PMID: 10648613
A cell line was generated that expresses the poliovirus 2A protease in an inducible manner. Tightly controlled expression was achieved by utilizing the muristerone A-regulated expression system. Upon induction, cleavage...
9.
Orian A, Schwartz A, Israel A, Whiteside S, Kahana C, Ciechanover A
Mol Cell Biol
. 1999 Apr;
19(5):3664-73.
PMID: 10207090
The ubiquitin proteolytic system plays a major role in a variety of basic cellular processes. In the majority of these processes, the target proteins are completely degraded. In one exceptional...
10.
Zelzer E, Levy Y, Kahana C, Shilo B, Rubinstein M, Cohen B
EMBO J
. 1998 Sep;
17(17):5085-94.
PMID: 9724644
Hypoxic stress induces the expression of genes associated with increased energy flux, including the glucose transporters Glut1 and Glut3, several glycolytic enzymes, nitric oxide synthase, tyrosine hydroxylase, erythropoietin and vascular...