C J McBain
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Explore the profile of C J McBain including associated specialties, affiliations and a list of published articles.
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52
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3906
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Recent Articles
1.
Akgul G, Abebe D, Yuan X, Auville K, McBain C
Sci Rep
. 2019 Apr;
9(1):5435.
PMID: 30931998
In the hippocampal CA1, caudal ganglionic eminence (CGE)-derived interneurons are recruited by activation of glutamatergic synapses comprising GluA2-containing calcium-impermeable AMPARs and exert inhibitory regulation of the local microcircuit. However, the...
2.
Chittajallu R, Wester J, Craig M, Barksdale E, Yuan X, Akgul G, et al.
Nat Commun
. 2017 Jul;
8(1):152.
PMID: 28751664
Appropriate integration of GABAergic interneurons into nascent cortical circuits is critical for ensuring normal information processing within the brain. Network and cognitive deficits associated with neurological disorders, such as schizophrenia,...
3.
Vargish G, Pelkey K, Yuan X, Chittajallu R, Collins D, Fang C, et al.
Mol Psychiatry
. 2016 Dec;
22(1):1.
PMID: 27994236
No abstract available.
4.
Vargish G, Pelkey K, Yuan X, Chittajallu R, Collins D, Fang C, et al.
Mol Psychiatry
. 2016 Mar;
22(1):56-67.
PMID: 26976041
Placental transfer of Δ9-tetrahydrocannabinol (THC) during pregnancy has the potential to interfere with endogenous cannabinoid (CB) regulation of fetal nervous system development in utero. Here we examined the effect of...
5.
Ho M, Ho T, Pelkey K, Pelletier J, Huganir R, Lacaille J, et al.
J Physiol
. 2009 Jul;
587(Pt 18):4441-54.
PMID: 19635819
Synaptic development is an activity-dependent process utilizing coordinated network activity to drive synaptogenesis and subsequent refinement of immature connections. Hippocampal CA3 pyramidal neurons (PYRs) exhibit intense burst firing (BF) early...
6.
Chittajallu R, Chen Y, Wang H, Yuan X, Ghiani C, Heckman T, et al.
Proc Natl Acad Sci U S A
. 2002 Feb;
99(4):2350-5.
PMID: 11854528
Proliferative oligodendrocyte progenitor cells (OPs) express large, delayed outward-rectifying K(+) currents (I(K)), whereas nondividing immature and mature oligodendrocytes display much smaller I(K). Here, we show that up-regulation of I(K) occurs...
7.
Atzori M, Lei S, Evans D, Kanold P, McIntyre O, McBain C
Nat Neurosci
. 2001 Nov;
4(12):1230-7.
PMID: 11694887
Sound features are blended together en route to the central nervous system before being discriminated for further processing by the cortical synaptic network. The mechanisms underlying this synaptic processing, however,...
8.
Rudy B, McBain C
Trends Neurosci
. 2001 Aug;
24(9):517-26.
PMID: 11506885
Analysis of the Kv3 subfamily of K(+) channel subunits has lead to the discovery of a new class of neuronal voltage-gated K(+) channels characterized by positively shifted voltage dependencies and...
9.
McBain C, Fisahn A
Nat Rev Neurosci
. 2001 Mar;
2(1):11-23.
PMID: 11253355
Local-circuit, gamma-aminobutyric acid-releasing inhibitory interneurons of the hippocampus and cortex have traditionally been considered as the regulators of principal neuron activity--the yin to the excitatory yang. Recent evidence indicates that,...
10.
Toth K, Suares G, Lawrence J, McBain C
J Neurosci
. 2000 Nov;
20(22):8279-89.
PMID: 11069934
The axons of the dentate gyrus granule cells, the so-called mossy fibers, innervate their inhibitory interneuron and pyramidal neuron targets via both anatomically and functionally specialized synapses. Mossy fiber synapses...