C J Joyner
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Explore the profile of C J Joyner including associated specialties, affiliations and a list of published articles.
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25
Citations
359
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Recent Articles
1.
Chahine Z, Abel S, Hollin T, Barnes G, Chung J, Daub M, et al.
Science
. 2024 Sep;
385(6716):eadm7966.
PMID: 39325875
We report the discovery of MED6-189, an analog of the kalihinol family of isocyanoterpene natural products that is effective against drug-sensitive and drug-resistant strains, blocking both asexual replication and sexual...
2.
Chahine Z, Abel S, Hollin T, Chung J, Barnes G, Daub M, et al.
bioRxiv
. 2023 Dec;
PMID: 38045341
Here we report the discovery of MED6-189, a new analogue of the kalihinol family of isocyanoterpene (ICT) natural products. MED6-189 is effective against drug-sensitive and -resistant strains blocking both intraerythrocytic...
3.
Maher S, Bakowski M, Vantaux A, Flannery E, Andolina C, Gupta M, et al.
bioRxiv
. 2023 Feb;
PMID: 36778461
Radical cure of malaria must include elimination of quiescent 'hypnozoite' forms in the liver; however, the only FDA-approved treatments are contraindicated in many vulnerable populations. To identify new drugs and...
4.
Galinski M, Lapp S, Peterson M, Ay F, Joyner C, Le Roch K, et al.
Parasitology
. 2017 Jul;
145(1):85-100.
PMID: 28712361
Antigenic variation in malaria was discovered in Plasmodium knowlesi studies involving longitudinal infections of rhesus macaques (M. mulatta). The variant proteins, known as the P. knowlesi Schizont Infected Cell Agglutination...
5.
Isefuku S, Joyner C, Reed A, Simpson A
J Orthop Res
. 2004 Oct;
22(6):1276-82.
PMID: 15475209
Distraction osteogenesis involves division of a bone and gradually pulling the bone ends apart. This delivers mechanical stimulation to mesenchymal cells in the distraction gap, where new bone is regenerated...
6.
Reed A, Joyner C, Isefuku S, Brownlow H, Simpson A
J Bone Joint Surg Br
. 2003 Jun;
85(4):604-10.
PMID: 12793572
Our aim was to develop a clinically relevant model of atrophic nonunion in the rat to test the hypothesis that the vessel density of atrophic nonunion reaches that of normal...
7.
Reed A, Joyner C, Brownlow H, Simpson A
J Orthop Res
. 2002 Jun;
20(3):593-9.
PMID: 12038636
A small proportion of fractures progress to non-union. Non-unions are routinely classified into two groups either hypertrophic or atrophic according to their radiological appearance. It is a common preconception that...
8.
Levy M, Joyner C, Virdi A, Reed A, Triffitt J, Simpson A, et al.
Bone
. 2001 Oct;
29(4):317-22.
PMID: 11595613
The presence of osteogenic progenitors in human skeletal muscle is suggested by the formation of ectopic bone in clinical and experimental conditions, but their direct identification has not yet been...
9.
Isefuku S, Joyner C, Simpson A
J Orthop Res
. 2001 Sep;
19(5):950-4.
PMID: 11562146
We examined the effects of rifampicin on osteoblast-like cells derived from adult human bone in vitro. Cancellous bone was collected from five different individuals during elective orthopaedic operations and cultured...
10.
Isefuku S, Joyner C, Simpson A
Bone
. 2000 Nov;
27(5):661-5.
PMID: 11062353
Distraction osteogenesis is both a valuable clinical technique and a useful tool for investigating the basic mechanisms involved in bone tissue regeneration. Here we describe the development of a murine...