C J Bench
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Explore the profile of C J Bench including associated specialties, affiliations and a list of published articles.
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46
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1680
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Recent Articles
11.
Rabiner E, Bhagwagar Z, Gunn R, Sargent P, Bench C, Cowen P, et al.
Am J Psychiatry
. 2001 Dec;
158(12):2080-2.
PMID: 11729033
Objective: Positron emission tomography (PET) was used to examine whether the dose of pindolol used to augment antidepressant medication achieves a significant occupancy of the serotonin type 1A (5-HT(1A)) autoreceptor...
12.
Montgomery A, Bench C, Young A, Hammers A, Gunn R, Bhagwagar Z, et al.
Biol Psychiatry
. 2001 Nov;
50(9):668-76.
PMID: 11704073
Background: The hypothalamic-pituitary-adrenal (HPA) axis and serotonergic system interact functionally. The modulatory effect of corticosteroids on 5-HT(1A) receptor number and function has been repeatedly demonstrated in preclinical studies suggesting that...
13.
Bench C, Price E, Dally M, Borgwardt R
Appl Anim Behav Sci
. 2001 Mar;
72(1):41-50.
PMID: 11259825
The objective of this study was to determine the effect of a single generation of artificial selection for sexual performance in rams on the sexual behavior and fecundity of their...
14.
Rabiner E, Gunn R, Castro M, Sargent P, Cowen P, Koepp M, et al.
Neuropsychopharmacology
. 2000 Aug;
23(3):285-93.
PMID: 10942852
A novel strategy for improving the treatment of depressive illness is augmentation of antidepressants with a 5-HT1(1A) autoreceptor antagonist. However, trials using the 5-HT1(1A)/beta-blocker pindolol are proving inconsistent. We report...
15.
Dye S, Spence S, Bench C, Hirsch S, Stefan M, Sharma T, et al.
Br J Psychiatry
. 2000 May;
175:367-74.
PMID: 10789305
Background: Positron emission tomography (PET) studies have revealed functional left superior temporal gyrus (STG) abnormalities in symptomatic schizophrenia during word generation. Aims: To discover if this dysfunction is present in...
16.
Barbenel D, Yusufi B, OShea D, Bench C
J Psychopharmacol
. 2000 Apr;
14(1):84-6.
PMID: 10757260
We describe the case of a patient who developed depression following bilateral orchidectomy for cryptorchidism. He was treated with a conventional selective serotonin reuptake inhibitor antidepressant, but continued to take...
17.
Sargent P, Kjaer K, Bench C, Rabiner E, Messa C, Meyer J, et al.
Arch Gen Psychiatry
. 2000 Feb;
57(2):174-80.
PMID: 10665620
Background: Pharmacological and postmortem investigations suggest that patients with major depressive disorder have alterations in function or density of brain serotonin1A (5-HT1A) receptors. The aim of the present study was...
18.
Gunn R, Sargent P, Bench C, Rabiner E, Osman S, Pike V, et al.
Neuroimage
. 1998 Nov;
8(4):426-40.
PMID: 9811559
[Carbonyl-11C]WAY-100635 is a promising PET radioligand for the 5-HT1A receptor, having demonstrated more favorable characteristics for in vivo imaging than the previously available [O-methyl-11C]WAY-100635. The current study evaluates different tracer...
19.
Osman S, Lundkvist C, Pike V, Halldin C, McCarron J, Swahn C, et al.
Nucl Med Biol
. 1998 Jun;
25(3):215-23.
PMID: 9620626
N-(2-(4-(2-Methoxy-phenyl)-1-piperazin-1-yl)ethyl)-N-(2-pyridyl)++ +cyclohexanecarboxamide (WAY-100635), labelled in its amido carbonyl group with 11C (t1/2 = 20.4 min), is a promising radioligand for the study of brain 5-HT1A receptors with positron emission tomography...
20.
Koepp M, Gunn R, Lawrence A, Cunningham V, Dagher A, Jones T, et al.
Nature
. 1998 Jun;
393(6682):266-8.
PMID: 9607763
Dopaminergic neurotransmission may be involved in learning, reinforcement of behaviour, attention, and sensorimotor integration. Binding of the radioligand 11C-labelled raclopride to dopamine D2 receptors is sensitive to levels of endogenous...