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C H Mody

Explore the profile of C H Mody including associated specialties, affiliations and a list of published articles. Areas
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Articles 37
Citations 823
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Recent Articles
1.
Woo T, Lim R, Heirali A, Acosta N, Rabin H, Mody C, et al.
Sci Rep . 2019 May; 9(1):6871. PMID: 31053725
A diverse microbiota exists within the airways of individuals with non-cystic fibrosis bronchiectasis (nCFB). How the lung microbiome evolves over time, and whether changes within the microbiome correlate with future...
2.
Mody C, Warren P
Can J Infect Dis . 2012 Feb; 10(2):147-55. PMID: 22346380
Objective: To provide a basic understanding of the mechanisms of host defense to pathogenic fungi. This will help physicians understand why some patients are predisposed to fungal infections and update...
3.
Pace E, Profita M, Melis M, Bonanno A, Paterno A, Mody C, et al.
Clin Exp Immunol . 2004 Mar; 135(3):519-27. PMID: 15008988
The pleural space is a virtual compartment between the lung and chest wall that becomes filled with fluid and inflammatory cells during a variety of respiratory diseases. Here, we study...
4.
Neely G, Robbins S, Amankwah E, Epelman S, Wong H, Spurrell J, et al.
J Immunol . 2001 Oct; 167(9):5011-7. PMID: 11673509
Although IL-15 shares many of the biological activities of IL-2, IL-2 expression is primarily under transcriptional regulation, while the mechanisms involved in the regulation of IL-15 are complex and not...
5.
Syme R, Spurrell J, Ma L, Green F, Mody C
Infect Immun . 2000 Oct; 68(11):6147-53. PMID: 11035718
In addition to eliciting antigen specific T-cell-mediated immunity, Cryptococcus neoformans possesses a mitogen (CnM) that activates naive T cells to proliferate. This mechanism of T-cell activation is accessory cell dependent...
6.
Epelman S, Bruno T, Neely G, Woods D, Mody C
Infect Immun . 2000 Jul; 68(8):4811-4. PMID: 10899895
Pseudomonas aeruginosa infection of cystic fibrosis patients causes lung damage that is substantially orchestrated by cytokines. In this study, multi-gene probe analysis was used to characterize the ability of the...
7.
Bruno T, Woods D, Mody C
J Leukoc Biol . 2000 Jun; 67(6):808-16. PMID: 10857853
Exoenzyme S from Pseudomonas aeruginosa is a unique T cell mitogen; it is a powerful immunostimulus that activates a large proportion of T cells, but results in delayed and reduced...
8.
Bestilny L, Gill M, Mody C, Riabowol K
AIDS . 2000 Jun; 14(7):771-80. PMID: 10839584
Objectives: HIV induces rapid turnover of T lymphocytes but whether this leads to replicative senescence of CD4+ and CD8+ cells and contributes to AIDS symptoms is unclear. The aim of...
9.
Bruno T, Woods D, Storey D, Mody C
Can J Microbiol . 1999 Sep; 45(7):607-11. PMID: 10497789
Exoenzyme S from P. aeruginosa DG1 and recombinant exoenzyme S derived from strain 388 have distinct characteristics, which has led to a controversy about their homology and their pathophysiologic consequences....
10.
Syme R, Bruno T, Kozel T, Mody C
Infect Immun . 1999 Aug; 67(9):4620-7. PMID: 10456908
Cell-mediated immunity is critical for the host defense to Cryptococcus neoformans, as demonstrated by numerous animal studies and the prevalence of the infection in AIDS patients. Previous studies have established...