C G Da Silva
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Explore the profile of C G Da Silva including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
161
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Recent Articles
1.
Da Silva C, Camps M, Li T, Chan A, Ossendorp F, Cruz L
Biomaterials
. 2019 Aug;
220:119417.
PMID: 31419588
To improve the efficacy of cancer vaccines we aimed to modulate the suppressive tumor microenvironment. In this study, the potential of intratumoral immune modulation with poly (I:C), Resiquimod (R848) and...
2.
Chung C, Da Silva C, Kralisch D, Chan A, Ossendorp F, Cruz L
J Control Release
. 2018 Jul;
285:56-66.
PMID: 30008371
Cancer immunotherapy is emerging as a candidate treatment modality for treating post-surgical metastasis and recurrences. Despite the great promises with therapeutic cancer vaccines and checkpoint blocking antibodies in pre-clinical studies,...
3.
Da Silva C, Peters G, Ossendorp F, Cruz L
Cancer Chemother Pharmacol
. 2017 Sep;
80(5):881-894.
PMID: 28887666
Purpose: The therapeutic efficacy of conventional chemotherapy against several solid tumors is generally limited and this is often due to the development of resistance or poor delivery of the drugs...
4.
Huis Int Veld R, Da Silva C, Kaijzel E, Chan A, Cruz L
Curr Pharm Des
. 2016 Dec;
23(13):1985-1992.
PMID: 28003012
The induction of immune tolerance towards self-antigens presents as a viable future strategy in the treatment of auto-immune diseases, including vasculitis and multiple sclerosis (MS). As specific targets are currently...
5.
Da Silva C, Rueda F, Lowik C, Ossendorp F, Cruz L
Biomaterials
. 2016 Jan;
83:308-20.
PMID: 26796043
Despite the significant increase in our knowledge on cancer initiation and progression, and the development of novel cancer treatments, overall patient survival rates have thus far only marginally improved. However,...
6.
Studer P, Da Silva C, Revuelta Cervantes J, Mele A, Csizmadia E, Siracuse J, et al.
Cell Death Differ
. 2015 May;
22(12):2068-77.
PMID: 25976305
Hepatic expression of A20, including in hepatocytes, increases in response to injury, inflammation and resection. This increase likely serves a hepatoprotective purpose. The characteristic unfettered liver inflammation and necrosis in...
7.
Da Silva C, Bueno A, Schuck P, Leipnitz G, Ribeiro C, Wannmacher C, et al.
Eur J Clin Invest
. 2003 Sep;
33(10):840-7.
PMID: 14511354
Background: Tissue accumulation of high amounts of D-2-hydroxyglutaric acid (DGA) is the biochemical hallmark of the inherited neurometabolic disorder D-2-hydroxyglutaric aciduria (DHGA). Patients affected by this disease usually present hypotonia,...
8.
Galli L, Volpini R, Costa R, Da Silva C, Coimbra T
Ren Fail
. 2001 Dec;
23(5):693-703.
PMID: 11725916
Several lines of evidence have suggested that renal handling of proteins in rats with several nephropathies may contribute to the tubulointerstitial damage observed in these animals. It has been suggested...
9.
BARONI E, Costa R, Da Silva C, Coimbra T
Nephron
. 2000 Mar;
84(3):248-57.
PMID: 10720896
In this study we investigated the effect of heparin on renal injury and renal transforming growth factor-beta (TGF-beta) production in adriamycin (AD)-injected rats. Thirty-nine female Wistar rats were injected with...
10.
Rotta L, Da Silva C, Perry M, Trindade V
Ann Nutr Metab
. 1999 Nov;
43(3):152-8.
PMID: 10545671
Background/aims: Undernutrition reduces the hypothalamic ganglioside concentration. This may be attributed to some modifications in the contents of precursors of sphingolipid biosynthesis in undernourished rats. The present study evaluated the...