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C E Lawrence

Explore the profile of C E Lawrence including associated specialties, affiliations and a list of published articles. Areas
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Articles 80
Citations 2428
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Recent Articles
21.
Qu K, McCue L, Lawrence C
Proc Int Conf Intell Syst Mol Biol . 1998 Oct; 6:131-9. PMID: 9783218
A Bayesian procedure for the simultaneous alignment and classification of sequences into subclasses is described. This Gibbs sampling algorithm iterates between an alignment step and a classification step. It employs...
22.
Lawrence C, Paterson J, Higgins L, MacDonald T, Kennedy M, Garside P
Eur J Immunol . 1998 Oct; 28(9):2672-84. PMID: 9754555
The relationship between intestinal pathology and immune expulsion of gastrointestinal nematodes remains controversial. Parasite expulsion is associated with intestinal pathology in several model systems and both of these phenomena are...
23.
Qu K, Martin D, Lawrence C
Protein Sci . 1998 May; 7(5):1092-105. PMID: 9605314
The pyridoxal-P binding sites of the two isoforms of human glutamate decarboxylase (GAD65 and GAD67) were modeled by using PROBE (a recently developed algorithm for multiple sequence alignment and database...
24.
Zhu J, Liu J, Lawrence C
Bioinformatics . 1998 Apr; 14(1):25-39. PMID: 9520499
The selection of a scoring matrix and gap penalty parameters continues to be an important problem in sequence alignment. We describe here an algorithm, the 'Bayes block aligner, which bypasses...
25.
Duthie S, Eckersall P, Addie D, Lawrence C, Jarrett O
Vet Rec . 1997 Oct; 141(12):299-303. PMID: 9330474
Feline infectious peritonitis (FIP) is notoriously difficult to differentiate from the many other diseases with similar clinical signs and at present the only conclusive diagnostic test is the histopathological examination...
26.
Dasgupta S, Iyer G, BRYANT S, Lawrence C, Bell J
Proteins . 1997 Aug; 28(4):494-514. PMID: 9261866
A survey was compiled of several characteristics of the intersubunit contacts in 58 oligomeric proteins, and of the intermolecular contracts in the lattice for 223 protein crystal structures. The total...
27.
Neuwald A, Liu J, Lipman D, Lawrence C
Nucleic Acids Res . 1997 May; 25(9):1665-77. PMID: 9108146
Biologists often gain structural and functional insights into a protein sequence by constructing a multiple alignment model of the family. Here a program called Probe fully automates this process of...
28.
Auger I, Bellisario R, Lawrence C
Early Hum Dev . 1997 Jan; 47(2):235-45. PMID: 9039971
A retrospective analysis of 400 newborns diagnosed with congenital primary hypothyroidism between 1983 and 1987 was conducted. Two distinct groups of cases were identified and characterized based on their newborn...
29.
Mannella C, Neuwald A, Lawrence C
J Bioenerg Biomembr . 1996 Apr; 28(2):163-9. PMID: 9132415
The mitochondrial channel VDAC is presumed to fold as a beta-barrel although the number and identity of transmembrane beta-strands in the protein are controversial. Previously, a novel multiple alignment algorithm...
30.
Neuwald A, Liu J, Lawrence C
Protein Sci . 1995 Aug; 4(8):1618-32. PMID: 8520488
The detection and alignment of locally conserved regions (motifs) in multiple sequences can provide insight into protein structure, function, and evolution. A new Gibbs sampling algorithm is described that detects...