C E Lawrence
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Explore the profile of C E Lawrence including associated specialties, affiliations and a list of published articles.
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80
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2428
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Recent Articles
1.
Ierna M, Scales H, Mueller C, Lawrence C
Infect Immun
. 2009 Jul;
77(9):3879-85.
PMID: 19564380
To study the specific role of transmembrane tumor necrosis factor (tmTNF) in protective and pathological responses against the gastrointestinal helminth Trichinella spiralis, we compared the immune responses of TNF-alpha/lymphotoxin alpha...
2.
Ierna M, Scales H, Saunders K, Lawrence C
Mucosal Immunol
. 2008 Dec;
1(2):147-55.
PMID: 19079172
Expulsion of the gastrointestinal nematode Trichinella spiralis is associated with Th2 responses and intestinal inflammation, which correlate with a marked mast cell (MC) response. To address the role of MC-derived...
3.
Scales H, Ierna M, Lawrence C
Parasite Immunol
. 2007 Jan;
29(2):81-91.
PMID: 17241396
T helper type 2 (Th2) responses have been shown to be important in protective responses to gastrointestinal (GI) helminth infections and in the development of the intestinal pathology accompanying expulsion...
4.
Boitelle A, Di Lorenzo C, Scales H, Devaney E, Kennedy M, Garside P, et al.
Int J Parasitol
. 2005 May;
35(7):765-75.
PMID: 15893319
We have previously found that co-immunisation with ovalbumin (OVA) and the body fluid of the helminth Ascaris suum inhibited an OVA-specific delayed type hypersensitivity (DTH) response by reducing OVA-specific CD4+...
5.
Thomas J, Touchman J, Blakesley R, Bouffard G, Beckstrom-Sternberg S, Margulies E, et al.
Nature
. 2003 Aug;
424(6950):788-93.
PMID: 12917688
The systematic comparison of genomic sequences from different organisms represents a central focus of contemporary genome analysis. Comparative analyses of vertebrate sequences can identify coding and conserved non-coding regions, including...
6.
Shekels L, Anway R, Lin J, Kennedy M, Garside P, Lawrence C, et al.
Dig Dis Sci
. 2001 Aug;
46(8):1757-64.
PMID: 11508679
Mucin hypersecretion is an important component of the immune response to gastrointestinal nematode infection. Two discrete types of mucin proteins exist in the mouse intestine, secretory Muc2 and membrane-bound Muc3....
7.
Ding Y, Lawrence C
Nucleic Acids Res
. 2001 Feb;
29(5):1034-46.
PMID: 11222752
Single-stranded regions in RNA secondary structure are important for RNA-RNA and RNA-protein interactions. We present a probability profile approach for the prediction of these regions based on a statistical algorithm...
8.
Hu W, Thompson W, Lawrence C, Derbyshire K
J Mol Biol
. 2001 Feb;
306(3):403-16.
PMID: 11178901
Like many transposons the bacterial insertion sequence IS903 was thought to insert randomly. However, using both genetic and statistical approaches, we have derived a target site for IS903 that is...
9.
McCue L, Thompson W, Carmack C, Ryan M, Liu J, Derbyshire V, et al.
Nucleic Acids Res
. 2001 Feb;
29(3):774-82.
PMID: 11160901
Toward the goal of identifying complete sets of transcription factor (TF)-binding sites in the genomes of several gamma proteobacteria, and hence describing their transcription regulatory networks, we present a phylogenetic...
10.
Lawrence C, Paterson J, Wei X, Liew F, Garside P, Kennedy M
J Immunol
. 2001 Feb;
164(8):4229-34.
PMID: 10754319
The relationship between intestinal pathology and immune expulsion of gastrointestinal (GI) nematodes remains controversial. Although immune expulsion of GI helminth parasites is usually associated with Th2 responses, the effector mechanisms...