C E Comment
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Explore the profile of C E Comment including associated specialties, affiliations and a list of published articles.
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14
Citations
145
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Recent Articles
1.
Fontenot A, Kotzin B, Comment C, Newman L
Am J Respir Cell Mol Biol
. 1998 May;
18(4):581-9.
PMID: 9533947
Chronic beryllium disease (CBD) is a granulomatous disorder characterized by the presence of noncaseating granulomas and mononuclear cell inflammation, occurring in 1 to 5% of people exposed to beryllium in...
2.
Holladay S, Comment C, Kwon J, Luster M
Toxicol Appl Pharmacol
. 1994 Nov;
129(1):53-60.
PMID: 7974496
Ethylene glycol monomethyl ether (EGME), which is extensively used in the chemical industries, has been associated with hematologic disorders in both humans and experimental animals. EGME is metabolized to the...
3.
Pollock P, Germolec D, Comment C, Rosenthal G, Luster M
Fundam Appl Toxicol
. 1994 Jan;
22(1):130-8.
PMID: 8125206
Mice with the severe combined immunodeficient (SCID) and triple-deficient (bg/nu/xid) mutations lack select populations of functional immune cells. Studies by several laboratories have demonstrated the ability to restore certain missing...
4.
Holladay S, Blaylock B, Comment C, Heindel J, Fox W, Korach K, et al.
Cell Immunol
. 1993 Nov;
152(1):131-42.
PMID: 8242756
Estrogens have been reported to modulate immunologic responses at both physiologic and pharmacologic concentrations. Treatment of experimental animals with the synthetic estrogen, diethylstilbesterol (DES), markedly decreases thymic cellularity, manifested histologically...
5.
Holladay S, Blaylock B, Comment C, Heindel J, Luster M
Toxicol Appl Pharmacol
. 1993 Jul;
121(1):8-14.
PMID: 8337703
Treatment of experimental animals with T-2 toxin has been found to markedly decrease thymic cellularity and to suppress cell-mediated immune function. Although T-2 toxin readily crosses the placenta, little is...
6.
Blaylock B, Kouchi Y, Comment C, Pollock P, Luster M
J Immunol
. 1993 Jun;
150(11):5135-43.
PMID: 8496607
T-2 toxin, a trichothecene mycotoxin, has previously been shown to alter immune functions and promote skin tumors. We demonstrate that topically applied T-2 toxin reduces the ear swelling response to...
7.
Luster M, Pait D, Portier C, Rosenthal G, Germolec D, Comment C, et al.
Toxicol Lett
. 1992 Dec;
64-65 Spec No:71-8.
PMID: 1471226
We have previously reported on the design and content of a screening battery using a "tier" approach for detecting potential immunosuppressive compounds in mice [1]. This battery was composed of...
8.
Comment C, Blaylock B, Germolec D, Pollock P, Kouchi Y, Brown H, et al.
J Pharmacol Exp Ther
. 1992 Sep;
262(3):1267-73.
PMID: 1527729
In addition to hepatic injury, thymic atrophy is a common observation in rodent subchronic toxicity studies. We have examined representative chemicals which produce thymic atrophy in rodents for their ability...
9.
Blaylock B, Holladay S, Comment C, Heindel J, Luster M
Toxicol Appl Pharmacol
. 1992 Feb;
112(2):207-13.
PMID: 1531708
We previously reported that thymic atrophy and reduced thymic cellularity associated with prenatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice are characterized by quantitative alerations in the number of thymocytes expressing...
10.
Blaylock B, Kouchi Y, Comment C, Corsini E, Rosenthal G, Luster M
J Immunol
. 1991 Oct;
147(7):2116-21.
PMID: 1833452
The mechanism of action of pentamidine isethionate, a diamidino compound used in the treatment of Pneumocystis carinii pneumonia, is unknown. We recently reported that this drug may inhibit the release...