C Dieguez
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Explore the profile of C Dieguez including associated specialties, affiliations and a list of published articles.
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Articles
312
Citations
5586
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Recent Articles
1.
Casado S, Varela-Miguens M, de Oliveira Diz T, Quintela-Vilarino C, Nogueiras R, Dieguez C, et al.
J Endocrinol Invest
. 2024 Feb;
47(8):2061-2074.
PMID: 38337094
Purpose: Liver-expressed antimicrobial peptide 2 (LEAP-2) has been recently identified as the endogenous non-competitive allosteric antagonist of the growth hormone secretagogue receptor 1a (GHSR1a). In rodents, LEAP-2 blunts ghrelin-induced feeding...
2.
Franssen D, Barroso A, Ruiz-Pino F, Vazquez M, Garcia-Galiano D, Castellano J, et al.
Metabolism
. 2020 Dec;
115:154460.
PMID: 33285180
Background: Reproduction is tightly coupled to body energy and metabolic status. GnRH neurons, master elements and final output pathway for the brain control of reproduction, directly or indirectly receive and...
3.
Brance M, Pons-Estel B, Quagliato N, Jorfen M, Berbotto G, Cortese N, et al.
Osteoporos Int
. 2020 Sep;
32(4):705-714.
PMID: 32974730
Introduction: To evaluate cortical and trabecular bone involvement of the hip in RA patients by dual-energy X-ray absorptiometry (DXA) and 3D analysis. The secondary end-point was to evaluate bone involvement...
4.
Tena-Sempere M, Barreiro M, Lage M, Dieguez C, Casanueva F
Expert Rev Endocrinol Metab
. 2019 Feb;
2(2):239-249.
PMID: 30754186
Gonadal development and function is sustained by the complex interaction of an array of regulatory signals that operate directly on the gonads and/or indirectly via modulation of gonadotropin secretion. During...
5.
Vazquez M, Toro C, Castellano J, Ruiz-Pino F, Roa J, Beiroa D, et al.
Nat Commun
. 2018 Oct;
9(1):4194.
PMID: 30305620
Puberty is regulated by epigenetic mechanisms and is highly sensitive to metabolic and nutritional cues. However, the epigenetic pathways mediating the effects of nutrition and obesity on pubertal timing are...
6.
Decara J, Rivera P, Arrabal S, Vargas A, Serrano A, Pavon F, et al.
Acta Physiol (Oxf)
. 2017 Dec;
222(4):e13008.
PMID: 29193738
Aim: To explore the cooperation of GLP-1 receptor and β3-adrenergic receptor (β3-AR)-mediated signalling in the control of fat mass/feeding behaviour by studying the effects of a combined therapy composed of...
7.
Muller T, Nogueiras R, Andermann M, Andrews Z, Anker S, Argente J, et al.
Mol Metab
. 2015 Jun;
4(6):437-60.
PMID: 26042199
Background: The gastrointestinal peptide hormone ghrelin was discovered in 1999 as the endogenous ligand of the growth hormone secretagogue receptor. Increasing evidence supports more complicated and nuanced roles for the...
8.
Tuduri E, Beiroa D, Porteiro B, Lopez M, Dieguez C, Nogueiras R
Diabetes Obes Metab
. 2015 May;
17(8):789-99.
PMID: 25962313
Aim: To investigate the role of brain glucagon-like peptide-1 (GLP-1) in pancreatic β-cell function. Methods: To determine the role of brain GLP-1 receptor (GLP-1R) on β-cell function, we administered intracerebroventricular...
9.
Folgueira C, Sanchez-Rebordelo E, Barja-Fernandez S, Leis R, Tovar S, Casanueva F, et al.
Eur J Nutr
. 2015 Mar;
55(2):529-536.
PMID: 25743370
Purpose: Uroguanylin (UGN) is a 16 amino acid peptide produced mainly by intestinal epithelial cells. Nutrients intake increases circulating levels of prouroguanylin that is processed and converted to UGN to...
10.
Martinez de Morentin P, Martinez-Sanchez N, Roa J, Ferno J, Nogueiras R, Tena-Sempere M, et al.
Curr Mol Med
. 2013 Nov;
14(1):3-21.
PMID: 24236459
Optimal cellular function and therefore organism's survival is determined by the sensitive and accurate convergence of energy and nutrient abundance to cell growth and division. Among other factors, this integration...