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C D Mandyam

Explore the profile of C D Mandyam including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 279
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Recent Articles
1.
Pearn M, Schilling J, Jian M, Egawa J, Wu C, Mandyam C, et al.
Br J Anaesth . 2018 Mar; 120(4):745-760. PMID: 29576115
Background: Exposure of the developing brain to propofol results in cognitive deficits. Recent data suggest that inhibition of neuronal apoptosis does not prevent cognitive defects, suggesting mechanisms other than neuronal...
2.
Galinato M, Lockner J, Fannon-Pavlich M, Sobieraj J, Staples M, Somkuwar S, et al.
Mol Psychiatry . 2017 Mar; 23(3):629-638. PMID: 28348387
Adult neurogenesis in the dentate gyrus (DG) is strongly influenced by drug-taking behavior and may have a role in the etiology of drug-seeking behavior. However, mechanistic studies on the relationship...
3.
Staples M, Somkuwar S, Mandyam C
Neuroscience . 2015 Jul; 305:248-56. PMID: 26220171
Recent evidence suggests that the behavioral benefits associated with voluntary wheel running in rodents may be due to modulation of glutamatergic transmission in the hippocampus, a brain region implicated in...
4.
Navarro A, Mandyam C
Neuroscience . 2015 Mar; 293:35-44. PMID: 25732140
In rodents, chronic intermittent ethanol vapor exposure (CIE) produces alcohol dependence, alters the structure and activity of pyramidal neurons and decreases the number of oligodendroglial progenitors in the medial prefrontal...
5.
Galinato M, Orio L, Mandyam C
Neuroscience . 2014 Dec; 286:97-108. PMID: 25463524
Methamphetamine exposure reduces hippocampal long-term potentiation (LTP) and neurogenesis and these alterations partially contribute to hippocampal maladaptive plasticity. The potential mechanisms underlying methamphetamine-induced maladaptive plasticity were identified in the present...
6.
Arguello A, Harburg G, Schonborn J, Mandyam C, Yamaguchi M, Eisch A
Neuroscience . 2008 Oct; 157(1):70-9. PMID: 18832014
Opiates, such as morphine, decrease neurogenesis in the adult hippocampal subgranular zone (SGZ), raising the possibility that decreased neurogenesis contributes to opiate-induced cognitive deficits. However, there is an incomplete understanding...
7.
Mandyam C, Harburg G, Eisch A
Neuroscience . 2007 Feb; 146(1):108-22. PMID: 17307295
Neurogenesis studies on the adult mouse hippocampal subgranular zone (SGZ) typically report increases or decreases in proliferation. However, key information is lacking about these proliferating SGZ precursors, from the fundamental--what...
8.
Mathis J, Mandyam C, Altememi G, Pasternak G, Standifer K
Neurosci Lett . 2001 Feb; 299(3):173-6. PMID: 11165763
kappa(3) opioid receptors have a unique binding and analgesic profile, as originally defined by naloxone benzoylhydrazone (NalBzoH). Although antisense studies demonstrated the close relationship between kappa(3) opioid and Orphan opioid...
9.
Mandyam C, Altememi G, Standifer K
Eur J Pharmacol . 2000 Aug; 402(1-2):R1-37. PMID: 10940375
The potential interactions of natively expressed mu-opioid and opioid receptor-like (ORL1) receptors were studied by exposing intact BE(2)-C cells to agonists or antagonists for 1 h. Pretreatment with the mu-opioid...