C C Naus
Overview
Explore the profile of C C Naus including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
80
Citations
2003
Followers
0
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Recent Articles
1.
Sin W, Aftab Q, Bechberger J, Leung J, Chen H, Naus C
Oncogene
. 2015 Jul;
35(12):1504-16.
PMID: 26165844
Reactive astrocytes are integral to the glioma microenvironment. Connexin43 (Cx43) is a major gap junction protein in astrocytes and its expression is enhanced significantly in glioma-associated astrocytes, especially at the...
2.
Freitas-Andrade M, Naus C
Neuroscience
. 2015 Apr;
323:207-21.
PMID: 25913636
The World Health Organization has predicted that by 2040 neurodegenerative diseases will overtake cancer to become the world's second leading cause of death after cardiovascular disease. This has sparked the...
3.
Decrock E, Krysko D, Vinken M, Kaczmarek A, Crispino G, Bol M, et al.
Cell Death Differ
. 2011 Nov;
19(6):947-57.
PMID: 22117194
Decades of research have indicated that gap junction channels contribute to the propagation of apoptosis between neighboring cells. Inositol 1,4,5-trisphosphate (IP₃) has been proposed as the responsible molecule conveying the...
4.
Mancuso M, Pasquali E, Leonardi S, Rebessi S, Tanori M, Giardullo P, et al.
Oncogene
. 2011 May;
30(45):4601-8.
PMID: 21602884
Ionizing radiation is a genotoxic agent and human carcinogen. Recent work has questioned long-held dogmas by showing that cancer-associated genetic alterations occur in cells and tissues not directly exposed to...
5.
Herrero-Gonzalez S, Gangoso E, Giaume C, Naus C, Medina J, Tabernero A
Oncogene
. 2010 Aug;
29(42):5712-23.
PMID: 20676131
One of the characteristics of gliomas is a decrease in the expression of connexin43, a protein that forms gap junctions. Restoring connexin43 expression in glioma cells reduces their exacerbated rate...
6.
Lai C, Bechberger J, Naus C
Oncogene
. 2009 Sep;
28(49):4402-8.
PMID: 19749789
Connexins (Cxs), the gap junction proteins, have been found to be downregulated in many types of cancers including gliomas. By restoring gap junctional communication in cancer cell models, the neoplastic...
7.
Decrock E, De Vuyst E, Vinken M, Van Moorhem M, Vranckx K, Wang N, et al.
Cell Death Differ
. 2008 Sep;
16(1):151-63.
PMID: 18820645
Gap junctions (GJs) have been demonstrated to communicate cell death signals from apoptotic to healthy cells, thereby spatially extending apoptosis. Before being incorporated into GJs, hemichannels (hemi-GJs) are normally closed...
8.
Bates D, Sin W, Aftab Q, Naus C
Glia
. 2007 Sep;
55(15):1554-64.
PMID: 17823969
Gliomas are particularly difficult to cure owing largely to their invasive nature. The neoplastic changes of astrocytes which give rise to these tumors frequently include a reduction of connexin43 (Cx43),...
9.
McLeod T, Bechberger J, Naus C
Cell Commun Adhes
. 2002 Jun;
8(4-6):441-5.
PMID: 12064632
Tumour cells often exhibit erratic cell growth, as well as decreased gap junctional intercellular communication (GJIC). C6 glioma cells are characterized by low levels of gap junction mRNA and protein,...
10.
Naus C, Ozog M, Bechberger J, Nakase T
Cell Commun Adhes
. 2002 Jun;
8(4-6):325-8.
PMID: 12064612
Glial-neuronal interactions have been implicated in both normal information processing and neuroprotection. One pathway of cellular interactions involves gap junctional intercellular communication (GJIC). In astrocytes, gap junctions are composed primarily...