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C Butts

Explore the profile of C Butts including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 743
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Bebb D, Agulnik J, Albadine R, Banerji S, Bigras G, Butts C, et al.
Curr Oncol . 2019 Sep; 26(4):e551-e557. PMID: 31548824
The ros1 kinase is an oncogenic driver in non-small-cell lung cancer (nsclc). Fusion events involving the gene are found in 1%-2% of nsclc patients and lead to deregulation of a...
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Juergens R, Mariano C, Jolivet J, Finn N, Rothenstein J, Reaume M, et al.
Curr Oncol . 2019 Jan; 25(6):384-392. PMID: 30607113
Background: Nivolumab was the first immuno-oncology agent available for the treatment of lung cancer in Canada. In the present study, we evaluated the real-world benefit of nivolumab in Canadian patients...
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Melosky B, Cheema P, Agulnik J, Albadine R, Bebb D, Blais N, et al.
Curr Oncol . 2018 Nov; 25(5):317-328. PMID: 30464681
Background: Inhibition of the anaplastic lymphoma kinase (alk) oncogenic driver in advanced non-small-cell lung carcinoma (nsclc) improves survival. In 2015, Canadian thoracic oncology specialists published a consensus guideline about the...
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Vokes E, Ready N, Felip E, Horn L, Burgio M, Antonia S, et al.
Ann Oncol . 2018 Feb; 29(4):959-965. PMID: 29408986
Background: Long-term data with immune checkpoint inhibitors in non-small-cell lung cancer (NSCLC) are limited. Two phase III trials demonstrated improved overall survival (OS) and a favorable safety profile with the...
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Cabanero M, Sangha R, Sheffield B, Sukhai M, Pakkal M, Kamel-Reid S, et al.
Curr Oncol . 2017 May; 24(2):111-119. PMID: 28490925
Starting in the early 2000s, non-small-cell lung cancer (nsclc) subtypes have evolved from being histologically described to molecularly defined. Management of lung adenocarcinomas now generally requires multiple molecular tests at...
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Kim J, Davis F, Butts C, Winget M
Clin Oncol (R Coll Radiol) . 2016 Jul; 28(12):750-759. PMID: 27357099
Aims: Very little is known regarding the time required to diagnose and treat patients with non-small cell lung cancer (NSCLC) in Canada. We sought to quantify diagnostic and treatment intervals...
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Melosky B, Agulnik J, Albadine R, Banerji S, Bebb D, Bethune D, et al.
Curr Oncol . 2016 Jun; 23(3):196-200. PMID: 27330348
Anaplastic lymphoma kinase (alk) is an oncogenic driver in non-small-cell lung cancer (nsclc). Chromosomal rearrangements involving the ALK gene occur in up to 4% of nonsquamous nsclc patients and lead...
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Mitchell P, Thatcher N, Socinski M, Wasilewska-Tesluk E, Horwood K, Szczesna A, et al.
Ann Oncol . 2015 Feb; 26(6):1134-1142. PMID: 25722382
Background: Tecemotide is a MUC1-antigen-specific cancer immunotherapy. The phase III START study did not meet its primary end point but reported notable survival benefit with tecemotide versus placebo in an...
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Butts C, Kamel-Reid S, Batist G, Chia S, Blanke C, Moore M, et al.
Curr Oncol . 2013 Oct; 20(5):e475-83. PMID: 24155644
The burden of cancer for Canadian citizens and society is large. New technologies have the potential to increase the use of genetic information in clinical decision-making, furthering prevention, surveillance, and...