C Bosquillon
Overview
Explore the profile of C Bosquillon including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
118
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0
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Recent Articles
1.
Nieto-Orellana A, Li H, Rosiere R, Wauthoz N, Williams H, Monteiro C, et al.
J Control Release
. 2019 Nov;
316:250-262.
PMID: 31678655
Pulmonary delivery is increasingly seen as an attractive, non-invasive route for the delivery of forthcoming protein therapeutics. In this context, here we describe protein complexes with a new 'complexing excipient'...
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3.
Mukherjee M, Cingolani E, Pritchard D, Bosquillon C
Eur J Pharm Sci
. 2017 May;
106:62-70.
PMID: 28549677
Increasing evidence suggests Organic Cation Transporters (OCT) might facilitate the absorption of inhaled bronchodilators, including salbutamol, across the lung epithelium. This is essentially scarred and inflamed in asthma. Accordingly, the...
4.
Polyethylene glycol-drug ester conjugates for prolonged retention of small inhaled drugs in the lung
Bayard F, Thielemans W, Pritchard D, Paine S, Young S, Backman P, et al.
J Control Release
. 2013 Aug;
171(2):234-40.
PMID: 23916883
Typically, inhaled drugs are rapidly absorbed into the bloodstream, which results in systemic side effects and a brief residence time in the lungs. PEGylation was evaluated as a novel strategy...
5.
Mukherjee M, Latif M, Pritchard D, Bosquillon C
J Pharmacol Toxicol Methods
. 2013 Jun;
68(2):184-189.
PMID: 23764373
Introduction: Organic cation transporters (OCT) have been shown to mediate the transport of inhaled drugs in bronchial epithelial cells and might have important physiological functions in the airway epithelium. However,...
6.
Hutter V, Hilgendorf C, Cooper A, Zann V, Pritchard D, Bosquillon C
Eur J Pharm Sci
. 2012 Jul;
47(2):481-9.
PMID: 22820031
A rat respiratory epithelial cell culture system for in vitro prediction of drug pulmonary absorption is currently lacking. Such a model may however enhance the understanding of interspecies differences in...
7.
Mukherjee M, Pritchard D, Bosquillon C
Int J Pharm
. 2012 Jan;
426(1-2):7-14.
PMID: 22265910
A physiologically pertinent in vitro model is urgently needed for probing interactions between inhaled drugs and the organic cation transporters (OCT) in the bronchial epithelium. This study evaluated OCT expression,...
8.
Salem L, Bosquillon C, Dailey L, Delattre L, Martin G, Evrard B, et al.
J Control Release
. 2009 Apr;
136(2):110-6.
PMID: 19331849
Cyclodextrins (CDs) are promising solubility enhancers for inhaled drug delivery. However, they have dose-dependent effects on the respiratory epithelium, which may have advantages for permeability enhancement but also gives rise...
9.
Bosquillon C, Lombry C, Preat V, Vanbever R
J Pharm Sci
. 2001 Dec;
90(12):2032-41.
PMID: 11745762
The objectives of this work were (i) to validate electrical zone sensing and laser diffraction for the analysis of primary particle size in the case of inhalation dry powders and...
10.
Bosquillon C, Lombry C, Preat V, Vanbever R
J Control Release
. 2001 Feb;
70(3):329-39.
PMID: 11182203
The objective of this study was to determine the effects of formulation excipients and physical characteristics of inhalation particles on their in vitro aerosolization performance, and thereby to maximize their...