C B Tara Moore
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Explore the profile of C B Tara Moore including associated specialties, affiliations and a list of published articles.
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21
Citations
297
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Recent Articles
11.
Courtney D, Atkinson S, Allen E, Moore J, Walsh C, Leslie Pedrioli D, et al.
Invest Ophthalmol Vis Sci
. 2014 May;
55(5):3352-60.
PMID: 24801514
Purpose: The aim of this study is to further assess our previously reported keratin 12 (K12)-Leu132Pro specific siRNA in silencing the mutant allele in Meesmann's Epithelial Corneal Dystrophy (MECD) in...
12.
Courtney D, Atkinson S, Moore J, Maurizi E, Serafini C, Pellegrini G, et al.
Invest Ophthalmol Vis Sci
. 2014 Jan;
55(2):977-85.
PMID: 24425855
Purpose: This study aimed to investigate the potency and specificity of short-interfering RNA (siRNA) treatment for TGFBI-Arg124Cys lattice corneal dystrophy type I (LCDI) using exogenous expression constructs in model systems...
13.
Moore J, Atkinson S, Azar D, Worthington J, Downes C, Courtney D, et al.
Br J Ophthalmol
. 2013 Nov;
98(2):270-4.
PMID: 24288393
Background/aims: Cross-linking of the cornea is usually carried out at a young age as a treatment to manage ectasia. The corneal limbal region contains delicate long-lived stem cells, which could...
14.
Allen E, Atkinson S, Liao H, Moore J, Leslie Pedrioli D, Smith F, et al.
Invest Ophthalmol Vis Sci
. 2012 Dec;
54(1):494-502.
PMID: 23233254
Purpose: To identify an allele-specific short interfering RNA (siRNA), against the common KRT12 mutation Arg135Thr in Meesmann epithelial corneal dystrophy (MECD) as a personalized approach to treatment. Methods: siRNAs against...
15.
Al-Ojali S, Moore C, Fernandez-Cabezudo M, Al-Ramadi B
Med Microbiol Immunol
. 2012 Jun;
202(1):49-61.
PMID: 22684724
C3H/HeJ mice carry a mutated allele of TLR4 gene (TLR4 ( d )) and thus are hyporesponsive to the lethal effects of lipopolysaccharide (LPS). Characteristically, however, the mice are also...
16.
Al-Ojali S, Moore C, Fernandez-Cabezudo M, Al-Ramadi B
Microb Pathog
. 2012 Mar;
52(6):326-35.
PMID: 22445817
Previously, we demonstrated that cell-cell communications via the CD40-CD154 pathway play a critical role in the induction of type 1 cytokine responses, including IL-12 and IFN-γ, which in turn greatly...
17.
Liao H, Irvine A, MacEwen C, Weed K, Porter L, Corden L, et al.
PLoS One
. 2011 Dec;
6(12):e28582.
PMID: 22174841
Background: Meesmann epithelial corneal dystrophy (MECD) is an inherited eye disorder caused by dominant-negative mutations in either keratins K3 or K12, leading to mechanical fragility of the anterior corneal epithelium,...
18.
McLean W, Moore C
Hum Mol Genet
. 2011 Sep;
20(R2):R189-97.
PMID: 21890491
The term 'keratin' is generally accepted to refer to the epithelial keratins of soft and hard epithelial tissues such as: skin, cornea, hair and nail. Since their initial characterization, the...
19.
Atkinson S, McGilligan V, Liao H, Szeverenyi I, Smith F, Moore C, et al.
J Invest Dermatol
. 2011 Jul;
131(10):2079-86.
PMID: 21716320
Epidermolysis bullosa simplex (EBS) is an incurable, inherited skin-blistering disorder predominantly caused by dominant-negative mutations in the genes encoding keratins K5 or K14. RNA interference, particularly in the form of...
20.
Reynolds A, Moore J, Naroo S, Moore C, Shah S
Clin Exp Ophthalmol
. 2010 Apr;
38(2):168-82.
PMID: 20398106
Corneal surface laser ablation procedures for the correction of refractive error have enjoyed a resurgence of interest, especially in patients with a possible increased risk of complications after lamellar surgery....