C Aagaard
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Explore the profile of C Aagaard including associated specialties, affiliations and a list of published articles.
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13
Citations
301
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Recent Articles
1.
Jenkins A, Gormley E, Gcebe N, Fosgate G, Conan A, Aagaard C, et al.
Prev Vet Med
. 2018 Mar;
152:16-22.
PMID: 29559101
Accurate diagnosis of tuberculosis in cattle may be compromised in areas where there are high rates of exposure to environmental/non-tuberculous mycobacteria (NTM). This cross reaction of immune responses to Mycobacterium...
2.
Aagaard C, Govaerts M, Meikle V, Gutierrez-Pabello J, McNair J, Andersen P, et al.
Prev Vet Med
. 2010 Jul;
96(3-4):161-9.
PMID: 20630607
Bovine tuberculosis (BTB) is a major animal health problem with zoonotic implications. Current control programs are based on test and slaughter strategies utilizing skin tests with tuberculins as antigens. The...
3.
Aagaard C, Govaerts M, Meikle V, Vallecillo A, Gutierrez-Pabello J, Suarez-Guemes F, et al.
J Clin Microbiol
. 2006 Sep;
44(12):4326-35.
PMID: 17005738
Bovine tuberculosis is a major problem in many countries; hence, new and better diagnostic tools are urgently needed. In this work, we have tested ESAT6, CFP10, PE13, PE5, MPB70, TB10.4,...
4.
Baskakov I, Aagaard C, Mehlhorn I, Wille H, Groth D, Baldwin M, et al.
Biochemistry
. 2000 Mar;
39(10):2792-804.
PMID: 10704232
The central event in the pathogenesis of prion diseases is a profound conformational change of the prion protein (PrP) from an alpha-helical (PrP(C)) to a beta-sheet-rich isoform (PrP(Sc)). The elucidation...
5.
Supattapone S, Bosque P, Muramoto T, Wille H, Aagaard C, Peretz D, et al.
Cell
. 1999 Apr;
96(6):869-78.
PMID: 10102274
A redacted prion protein (PrP) of 106 amino acids with two large deletions was expressed in transgenic (Tg) mice deficient for wild-type (wt) PrP (Prnp0/0) and supported prion propagation. RML...
6.
Aagaard C, Semionenkov M, Garrett R
Trends Biochem Sci
. 1997 Sep;
22(9):326-31.
PMID: 9301331
Until recently, it appeared that archaeal introns were spliced by a process specific to the archaeal domain in which an endoribonuclease cuts a 'bulge-helix-bulge' motif that forms at exon-intron junctions....
7.
Aagaard C, Awayez M, Garrett R
Nucleic Acids Res
. 1997 Apr;
25(8):1523-30.
PMID: 9092657
I- Dmo I is a homing enzyme of the LAGLI-DADG type that recognizes up to 20 bp of DNA and is encoded by an archaeal intron of the hyperthermophilic archaeon...
8.
Aagaard C, Leviev I, Aravalli R, Forterre P, Prieur D, Garrett R
FEMS Microbiol Rev
. 1996 May;
18(2-3):93-104.
PMID: 8639332
Although there are currently no cloning and expression vectors available for archaeal hyperthermophiles, small cryptic plasmids have been characterized for these organisms as well as viruses and introns capable of...
9.
Aagaard C, Dalgaard J, Garrett R
Proc Natl Acad Sci U S A
. 1995 Dec;
92(26):12285-9.
PMID: 8618886
Some intron-containing rRNA genes of archaea encode homing-type endonucleases, which facilitate intron insertion at homologous sites in intron- alleles. These archaeal rRNA genes, in contrast to their eukaryotic counterparts, are...
10.
Aagaard C, Phan H, Trevisanato S, Garrett R
J Bacteriol
. 1994 Dec;
176(24):7744-7.
PMID: 8002603
Development of transformable vectors for thermophilic archaea requires the characterization of appropriate selectable marker genes. Many antibiotic inhibitors of protein biosynthesis are known to bind to rRNA; therefore, we screened...