Alpha 2.0
Login Register
» Authors » C A Svitek

C A Svitek

Explore the profile of C A Svitek including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 15
Citations 276
Followers 0
Related Specialties
Endocrinology
Biochemistry
Molecular Biology
Top 10 Co-Authors
R M OBrien
R S Streeper
J K Goldman
J K Oeser
J C Hutton
S C Chapman
J E Ayala
L A HORNBUCKLE
C C Martin
L J Bischof
Published In
J Biol Chem
Diabetes
J Mol Endocrinol
Proc Natl Acad Sci U S A
Am J Physiol Endocrinol Metab
Affiliations
Soon will be listed here.
Recent Articles
1.
Insulin-mediated activation of activator protein-1 through the mitogen-activated protein kinase pathway stimulates collagenase-1 gene transcription in the MES 13 mesangial cell line
Ayala J, Boustead J, Chapman S, Svitek C, Oeser J, Robey R, et al.
J Mol Endocrinol . 2004 Aug; 33(1):263-80. PMID: 15291758
The initial stages of diabetic nephropathy are characterized, in part, by expansion of the mesangial matrix and thickening of the glomerular basement membrane which are caused by increased extracellular matrix...
2.
Identification and characterization of a cDNA and the gene encoding the mouse ubiquitously expressed glucose-6-phosphatase catalytic subunit-related protein
Boustead J, Martin C, Oeser J, Svitek C, Hunter S, Hutton J, et al.
J Mol Endocrinol . 2004 Feb; 32(1):33-53. PMID: 14765991
Glucose-6-phosphatase (G6Pase) catalyzes the final step in the gluconeogenic and glycogenolytic pathways, the hydrolysis of glucose-6-phosphate (G6P) to glucose and phosphate. This paper describes the identification and characterization of a...
3.
Identification and characterization of a human cDNA and gene encoding a ubiquitously expressed glucose-6-phosphatase catalytic subunit-related protein
Martin C, Oeser J, Svitek C, Hunter S, Hutton J, OBrien R
J Mol Endocrinol . 2002 Oct; 29(2):205-22. PMID: 12370122
Glucose-6-phosphatase (G6Pase) catalyzes the final step in the gluconeogenic and glycogenolytic pathways, the hydrolysis of glucose-6-phosphate (G6P) to glucose and phosphate. This paper describes the identification and characterization of a...
4.
Selective tonic inhibition of G-6-Pase catalytic subunit, but not G-6-P transporter, gene expression by insulin in vivo
HORNBUCKLE L, Edgerton D, Ayala J, Svitek C, Oeser J, Neal D, et al.
Am J Physiol Endocrinol Metab . 2001 Sep; 281(4):E713-25. PMID: 11551847
The regulation of glucose-6-phosphatase (G-6-Pase) catalytic subunit and glucose 6-phosphate (G-6-P) transporter gene expression by insulin in conscious dogs in vivo and in tissue culture cells in situ were compared....
5.
Cloning and characterization of the human and rat islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP) genes
Martin C, Bischof L, Bergman B, HORNBUCKLE L, Hilliker C, Frigeri C, et al.
J Biol Chem . 2001 Apr; 276(27):25197-207. PMID: 11297555
Islet-specific glucose-6-phosphatase (G6Pase) catalytic subunit-related protein (IGRP) is a homolog of the catalytic subunit of G6Pase, the enzyme that catalyzes the terminal step of the gluconeogenic pathway. Its catalytic activity,...
6.
Protein kinase A phosphorylates hepatocyte nuclear factor-6 and stimulates glucose-6-phosphatase catalytic subunit gene transcription
Streeper R, HORNBUCKLE L, Svitek C, Goldman J, Oeser J, OBrien R
J Biol Chem . 2001 Mar; 276(22):19111-8. PMID: 11279202
Glucose-6-phosphatase is a multicomponent system that catalyzes the terminal step in gluconeogenesis. To examine the effect of the cAMP signal transduction pathway on expression of the gene encoding the mouse...
7.
Characterization of the mouse islet-specific glucose-6-phosphatase catalytic subunit-related protein gene promoter by in situ footprinting: correlation with fusion gene expression in the islet-derived betaTC-3 and hamster insulinoma tumor cell lines
Bischof L, Martin C, Svitek C, Stadelmaier B, HORNBUCKLE L, Goldman J, et al.
Diabetes . 2001 Mar; 50(3):502-14. PMID: 11246869
Glucose-6-phosphatase (G6Pase) is a multicomponent system located in the endoplasmic reticulum comprising a catalytic subunit and transporters for glucose-6-phosphate, inorganic phosphate, and glucose. We have recently cloned a novel gene...
8.
Differential role of hepatocyte nuclear factor-1 in the regulation of glucose-6-phosphatase catalytic subunit gene transcription by cAMP in liver- and kidney-derived cell lines
Streeper R, Svitek C, Goldman J, OBrien R
J Biol Chem . 2000 Apr; 275(16):12108-18. PMID: 10766845
In liver and kidney, the terminal step in gluconeogenesis is catalyzed by glucose-6-phosphatase. To examine the effect of the cAMP signal transduction pathway on transcription of the gene encoding the...
9.
Conservation of an insulin response unit between mouse and human glucose-6-phosphatase catalytic subunit gene promoters: transcription factor FKHR binds the insulin response sequence
Ayala J, Streeper R, Desgrosellier J, Durham S, Suwanichkul A, Svitek C, et al.
Diabetes . 1999 Sep; 48(9):1885-9. PMID: 10480625
Because overexpression of the glucose-6-phosphatase catalytic subunit (G-6-Pase) in both type 1 and type 2 diabetes may contribute to the characteristic increased rate of hepatic glucose production, we have investigated...
10.
Multiple promoter elements are required for the stimulatory effect of insulin on human collagenase-1 gene transcription. Selective effects on activator protein-1 expression may explain the quantitative difference in insulin and phorbol ester action
Chapman S, Ayala J, Streeper R, Culbert A, EATON E, Svitek C, et al.
J Biol Chem . 1999 Jun; 274(26):18625-34. PMID: 10373474
Several of the complications seen in patients with both type I and type II diabetes mellitus are associated with alterations in the expression of matrix metalloproteinases. To identify the cis-acting...