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C A Mathews

Explore the profile of C A Mathews including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 17
Citations 508
Followers 0
Related Specialties
Psychiatry
Psychology
Neurology
Top 10 Co-Authors
J M Scharf
V I Reus
D C Cath
N B Freimer
D Yu
E Fournier
L Osiecki
J A Knowles
J A Fagerness
T L Lowe
Published In
Psychol Med
Gynecol Oncol
Mol Psychiatry
Arch Dermatol
Proc Natl Acad Sci U S A
Affiliations
Soon will be listed here.
Recent Articles
1.
The efficacy and safety of mirvetuximab soravtansine in FRα-positive, third-line and later, recurrent platinum-sensitive ovarian cancer: the single-arm phase II PICCOLO trial
Alvarez Secord A, Lewin S, Murphy C, Cecere S, Barquin A, Galvez-Montosa F, et al.
Ann Oncol . 2024 Dec; 36(3):321-330. PMID: 39617145
Background: Mirvetuximab soravtansine-gynx (MIRV) is a first-in-class, folate receptor alpha (FRα)-targeting antibody-drug conjugate with United States Food and Drug Administration approval for FRα-positive platinum-resistant ovarian cancer. PICCOLO is a phase...
2.
A phase Ib/II and pharmacokinetic study of EP0057 (formerly CRLX101) in combination with weekly paclitaxel in patients with recurrent or persistent epithelial ovarian, fallopian tube, or primary peritoneal cancer
Duska L, Krasner C, OMalley D, Hays J, Modesitt S, Mathews C, et al.
Gynecol Oncol . 2021 Jan; 160(3):688-695. PMID: 33390325
Background: EP0057 (formerly CRLX101) is an investigational nanoparticle-drug conjugate (NDC) of a cyclodextrin-based polymer backbone plus camptothecin, a topoisomerase-1 inhibitor. Prior studies showed efficacy in recurrent or persistent, epithelial ovarian,...
3.
Genetic and phenotypic overlap of specific obsessive-compulsive and attention-deficit/hyperactive subtypes with Tourette syndrome
Hirschtritt M, Darrow S, Illmann C, Osiecki L, Grados M, Sandor P, et al.
Psychol Med . 2017 Jun; 48(2):279-293. PMID: 28651666
Background: The unique phenotypic and genetic aspects of obsessive-compulsive (OCD) and attention-deficit/hyperactivity disorder (ADHD) among individuals with Tourette syndrome (TS) are not well characterized. Here, we examine symptom patterns and...
4.
Heritability of tic disorders: a twin-family study
Zilhao N, Olthof M, Smit D, Cath D, Ligthart L, Mathews C, et al.
Psychol Med . 2016 Dec; 47(6):1085-1096. PMID: 27974054
Background: Genetic-epidemiological studies that estimate the contributions of genetic factors to variation in tic symptoms are scarce. We estimated the extent to which genetic and environmental influences contribute to tics,...
5.
Error-related brain activity dissociates hoarding disorder from obsessive-compulsive disorder
Mathews C, Perez V, Roach B, Fekri S, Vigil O, Kupferman E, et al.
Psychol Med . 2015 Sep; 46(2):367-79. PMID: 26415671
Background: Obsessive-compulsive disorder (OCD) is associated with an abnormally large error-related negativity (ERN), an electrophysiological measure of error monitoring in response to performance errors, but it is unclear if hoarding...
6.
Parental mood during pregnancy and post-natally is associated with offspring risk of Tourette syndrome or chronic tics: prospective data from the Avon Longitudinal Study of Parents and Children (ALSPAC)
Ben-Shlomo Y, Scharf J, Miller L, Mathews C
Eur Child Adolesc Psychiatry . 2015 Jul; 25(4):373-81. PMID: 26174227
Little is known about risk factors for Tourette syndrome (TS) and chronic tic disorders (CT) but maternal psychological morbidity in pregnancy may be associated with TS/CT. We examined whether pre-...
7.
Partitioning the etiology of hoarding and obsessive-compulsive symptoms
Mathews C, Delucchi K, Cath D, Willemsen G, Boomsma D
Psychol Med . 2014 Jul; 44(13):2867-76. PMID: 25066062
Background: Until recently, hoarding was considered an obsessive-compulsive symptom (OCS). However, current evidence suggests that these two phenotypes may be clinically, and perhaps etiologically, distinct. Both hoarding and OCS have...
8.
Meta-analysis of association between obsessive-compulsive disorder and the 3' region of neuronal glutamate transporter gene SLC1A1
Stewart S, Mayerfeld C, Arnold P, Crane J, ODushlaine C, Fagerness J, et al.
Am J Med Genet B Neuropsychiatr Genet . 2013 Apr; 162B(4):367-79. PMID: 23606572
The neuronal glutamate transporter gene SLC1A1 is a candidate gene for obsessive-compulsive disorder (OCD) based on linkage studies and convergent evidence implicating glutamate in OCD etiology. The 3' end of...
9.
Genome-wide association study of Tourette's syndrome
Scharf J, Yu D, Mathews C, Neale B, Stewart S, Fagerness J, et al.
Mol Psychiatry . 2012 Aug; 18(6):721-8. PMID: 22889924
Tourette's syndrome (TS) is a developmental disorder that has one of the highest familial recurrence rates among neuropsychiatric diseases with complex inheritance. However, the identification of definitive TS susceptibility genes...
10.
Genome-wide association study of obsessive-compulsive disorder
Stewart S, Yu D, Scharf J, Neale B, Fagerness J, Mathews C, et al.
Mol Psychiatry . 2012 Aug; 18(7):788-98. PMID: 22889921
Obsessive-compulsive disorder (OCD) is a common, debilitating neuropsychiatric illness with complex genetic etiology. The International OCD Foundation Genetics Collaborative (IOCDF-GC) is a multi-national collaboration established to discover the genetic variation...