C A Genco
Overview
Explore the profile of C A Genco including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
54
Citations
1748
Followers
0
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Recent Articles
1.
Michaud D, Kelsey K, Papathanasiou E, Genco C, Giovannucci E
Ann Oncol
. 2016 Jan;
27(5):941-7.
PMID: 26811350
Background: Periodontal disease has a direct impact on the immune response and has been linked to several chronic diseases, including atherosclerosis and stroke. Few studies have examined the association between...
2.
Slocum C, Kramer C, Genco C
J Intern Med
. 2016 Jan;
280(1):114-28.
PMID: 26791914
Cardiovascular disease is an inflammatory disorder characterized by the progressive formation of plaque in coronary arteries, termed atherosclerosis. It is a multifactorial disease that is one of the leading causes...
3.
Shaik-Dasthagirisaheb Y, Huang N, Weinberg E, Shen S, Genco C, Gibson 3rd F
J Periodontal Res
. 2014 May;
50(1):89-102.
PMID: 24862405
Background And Objective: Periodontal disease is a highly complex chronic inflammatory disease of the oral cavity. Multiple factors influence periodontal disease, including socio-economic status, genetics and age; however, inflammation elicited...
4.
Hayashi C, Gudino C, Gibson 3rd F, Genco C
Mol Oral Microbiol
. 2010 Oct;
25(5):305-16.
PMID: 20883220
A hallmark of infection with the gram-negative pathogen Porphyromonas gingivalis is the induction of a chronic inflammatory response. P. gingivalis induces a local chronic inflammatory response that results in oral...
5.
Follows S, Murlidharan J, Massari P, Wetzler L, Genco C
Infect Immun
. 2009 Jun;
77(9):3602-10.
PMID: 19546192
Several microbial pathogens can modulate the host apoptotic response to infection, which may contribute to immune evasion. Various studies have reported that infection with the sexually transmitted disease pathogen Neisseria...
6.
Gibson 3rd F, Yumoto H, Takahashi Y, Chou H, Genco C
J Dent Res
. 2006 Jan;
85(2):106-21.
PMID: 16434728
Periodontal diseases are a group of diseases that lead to erosion of the hard and soft tissues of the periodontium, which, in severe cases, can result in tooth loss. Anecdotal...
7.
Gyurko R, Shoji H, Battaglino R, Boustany G, Gibson 3rd F, Genco C, et al.
Bone
. 2005 Mar;
36(3):472-9.
PMID: 15777672
The role of inducible nitric oxide synthase (iNOS) in bone development and bacterially induced periodontal bone loss was examined using mice with targeted mutation of the iNOS gene. Femurs of...
8.
Gibson 3rd F, Genco C
Infect Immun
. 2001 Nov;
69(12):7959-63.
PMID: 11705986
The arginine gingipains RgpA and RgpB of Porphyromonas gingivalis are well-documented virulence factors of this organism. Structurally, RgpA and RgpB have nearly identical catalytic domains, while RgpA possesses an additional...
9.
Sroka A, Sztukowska M, Potempa J, Travis J, Genco C
J Bacteriol
. 2001 Sep;
183(19):5609-16.
PMID: 11544223
Porphyromonas gingivalis can use hemoglobin bound to haptoglobin and heme complexed to hemopexin as heme sources; however, the mechanism by which hemin is released from these proteins has not been...
10.
Olczak T, Dixon D, Genco C
J Bacteriol
. 2001 Sep;
183(19):5599-608.
PMID: 11544222
Previous genetic and biochemical studies have confirmed that hemoglobin and hemin utilization in Porphyromonas gingivalis is mediated by the outer membrane hemoglobin and heme receptor HmuR, as well as gingipain...