C A Fornal
Overview
Explore the profile of C A Fornal including associated specialties, affiliations and a list of published articles.
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29
Citations
784
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Recent Articles
1.
Fornal C, Metzler C, Mirescu C, Stein S, Jacobs B
Neuropsychopharmacology
. 2001 Dec;
25(6):858-70.
PMID: 11750179
St. John's wort is widely used as an herbal remedy for depression. Although its mechanism of action remains unknown, some evidence suggests that St. John's wort might act via brain...
2.
Bjorvatn B, Fornal C, Martin F, Metzler C, Jacobs B
Eur J Pharmacol
. 2000 Sep;
404(1-2):121-32.
PMID: 10980270
The therapeutic efficacy of antidepressant drugs that inhibit the reuptake of serotonin (5-hydroxytryptamine, 5-HT) may be enhanced by blocking their indirect activation of 5-HT(1A) autoreceptors, which mediate feedback inhibition of...
3.
Fornal C, Metzler C, Jacobs B
Neuroscience
. 2000 Jun;
98(2):301-9.
PMID: 10854761
Brain serotonin has long been implicated in the regulation of body temperature, although its precise role is not completely understood. The present study examined the effects of environmental cooling (4-8...
4.
Fornal C, Martin F, Metzler C, Jacobs B
J Pharmacol Exp Ther
. 1999 Sep;
291(1):229-38.
PMID: 10490909
Clinical studies have shown that pindolol can enhance the effects of antidepressant drugs, presumably by acting as an antagonist at somatodendritic 5-hydroxytryptamine (5-HT)(1A) autoreceptors, which regulate the firing rate of...
5.
Fornal C, Martin F, Metzler C, Jacobs B
J Pharmacol Exp Ther
. 1999 Sep;
291(1):220-8.
PMID: 10490908
The ability of pindolol to enhance the clinical antidepressant response to selective serotonin reuptake inhibitors (SSRIs) is generally attributed to a blockade of the feedback inhibition of serotonergic neuronal activity...
6.
Fornal C, Martin F, Mendlin A, Metzler C, Bjorvatn B, Jacobs B
Eur J Pharmacol
. 1999 Aug;
377(2-3):187-91.
PMID: 10456429
The effects of pindolol, a beta-adrenoceptor blocker/putative 5-hydroxytryptamine (5-HT)1A/1B antagonist, on both the single-unit activity of serotonergic neurons in the dorsal raphe nucleus (DRN) and extracellular 5-HT levels in the...
7.
Jacobs B, Fornal C
Neuropsychopharmacology
. 1999 Aug;
21(2 Suppl):9S-15S.
PMID: 10432483
Brain serotonergic neurons display a distinctive slow and regular discharge pattern in behaving animals. This activity gradually declines across the arousal-waking sleep cycle, becoming virtually silent during rapid eye movement...
8.
Bjorvatn B, Fornal C, Martin F, Metzler C, Jacobs B
Eur J Pharmacol
. 1998 Oct;
356(2-3):167-78.
PMID: 9774246
The effects of the putative 5-HT1A receptor antagonist 4-iodo-N-[2-[4-(methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinyl-benzam ide (p-MPPI) were examined on the activity of serotonergic dorsal raphe nucleus neurons in freely moving cats. Systemic administration of p-MPPI...
9.
Jacobs B, Fornal C
Curr Opin Neurobiol
. 1998 Feb;
7(6):820-5.
PMID: 9464975
The activity of brain serotonergic neurons in both the pontine-mesencephalic and medullary groups is positively correlated with the level of behavioral arousal and/or the behavioral state. This, in turn, appears...
10.
Gardner J, Fornal C, Jacobs B
Neuropsychopharmacology
. 1997 Aug;
17(2):72-81.
PMID: 9252982
Total sleep deprivation (TSD) for one or more nights produces a rapid antidepressant response in humans. Since most pharmacological treatments for depression increase brain serotonin neurotransmission, the purpose of the...