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» Authors » C A Del Vecchio

C A Del Vecchio

Explore the profile of C A Del Vecchio including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 3
Citations 100
Followers 0
Related Specialties
Oncology
Molecular Biology
Top 10 Co-Authors
A J Wong
A Merlo
H Vogel
A M Seddon
S A Khelwatty
T Florio
S Essapen
A K Godwin
C P Giacomini
S Eccles
Published In
Oncogene
Br J Cancer
Affiliations
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Recent Articles
1.
EGFRvIII gene rearrangement is an early event in glioblastoma tumorigenesis and expression defines a hierarchy modulated by epigenetic mechanisms
Del Vecchio C, Giacomini C, Vogel H, Jensen K, Florio T, Merlo A, et al.
Oncogene . 2012 Jul; 32(21):2670-81. PMID: 22797070
Amplification and rearrangements of the epidermal growth factor receptor (EGFR) gene are frequently found in glioblastoma multiforme (GBM). The most common variant is EGFR variant III (EGFRvIII). Research suggests that...
2.
Immunohistochemical discrimination of wild-type EGFR from EGFRvIII in fixed tumour specimens using anti-EGFR mAbs ICR9 and ICR10
Modjtahedi H, Khelwatty S, Kirk R, Seddon A, Essapen S, Del Vecchio C, et al.
Br J Cancer . 2012 Feb; 106(5):883-8. PMID: 22315050
Background: The human epidermal growth factor receptor (EGFR) is an important therapeutic target in oncology, and three different types of EGFR inhibitors have been approved for the treatment of cancer...
3.
The role of the c-Jun N-terminal kinase 2-α-isoform in non-small cell lung carcinoma tumorigenesis
Nitta R, Del Vecchio C, Chu A, Mitra S, Godwin A, Wong A
Oncogene . 2010 Sep; 30(2):234-44. PMID: 20871632
The c-Jun N-terminal kinases (JNKs) are members of the mitogen-activated protein kinase family and have been implicated in tumorigenesis. One isoform in particular, JNK2α, has been shown to be frequently...