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Bryn Eagleson

Explore the profile of Bryn Eagleson including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 222
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Recent Articles
1.
Zhou W, Hinoue T, Barnes B, Mitchell O, Iqbal W, Lee S, et al.
Cell Genom . 2022 Jul; 2(7). PMID: 35873672
We have developed a mouse DNA methylation array that contains 296,070 probes representing the diversity of mouse DNA methylation biology. We present a mouse methylation atlas as a rich reference...
2.
Kenyon E, Westerhuis J, Volk M, Hix J, Chakravarty S, Claucherty E, et al.
Breast Cancer Res . 2019 Nov; 21(1):129. PMID: 31779648
Background: Prophylactic mastectomy is the most effective intervention to prevent breast cancer. However, this major surgery has life-changing consequences at the physical, emotional, psychological, and social levels. Therefore, only high-risk...
3.
Dischinger P, Tovar E, Essenburg C, Madaj Z, Gardner E, Callaghan M, et al.
NPJ Breast Cancer . 2018 Sep; 4:29. PMID: 30182054
The key negative regulatory gene of the RAS pathway, , is mutated or deleted in numerous cancer types and is associated with increased cancer risk and drug resistance. Even though...
4.
Zhang Y, Staal B, Essenburg C, Su Y, Kang L, West R, et al.
Cancer Res . 2010 Jul; 70(17):6880-90. PMID: 20643778
The hepatocyte growth factor (HGF)-MET pathway supports several hallmark cancer traits, and it is frequently activated in a broad spectrum of human cancers (http://www.vai.org/met/). With the development of many cancer...
5.
Monks D, Johansen J, Mo K, Rao P, Eagleson B, Yu Z, et al.
Proc Natl Acad Sci U S A . 2007 Nov; 104(46):18259-64. PMID: 17984063
We created transgenic mice that overexpress WT androgen receptor (AR) exclusively in their skeletal muscle fibers. Unexpectedly, these mice display androgen-dependent muscle weakness and early death, show changes in muscle...