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Bryan R Becklund

Explore the profile of Bryan R Becklund including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 446
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Recent Articles
1.
Langenhorst D, Tabares P, Gulde T, Becklund B, Berr S, Surh C, et al.
Front Immunol . 2018 Feb; 8:1985. PMID: 29441059
In rodents, low doses of CD28-specific superagonistic monoclonal antibodies (CD28 superagonists, CD28SA) selectively activate regulatory T cells (Treg). This observation has recently been extended to humans, suggesting an option for...
2.
Becklund B, Purton J, Ramsey C, Favre S, Vogt T, Martin C, et al.
Sci Rep . 2016 Aug; 6:30842. PMID: 27480406
Aging is associated with a gradual loss of naïve T cells and a reciprocal increase in the proportion of memory T cells. While reduced thymic output is important, age-dependent changes...
3.
Becklund B, Severson K, Vang S, Deluca H
Proc Natl Acad Sci U S A . 2010 Mar; 107(14):6418-23. PMID: 20308557
Although the exact cause of multiple sclerosis (MS) is unknown, a number of genetic and environmental factors are thought to influence MS susceptibility. One potential environmental factor is sunlight and...
4.
Wang Y, Becklund B, Deluca H
Arch Biochem Biophys . 2009 Dec; 494(2):166-77. PMID: 19951695
The active form of vitamin D, 1alpha,25-dihydroxyvitamin D3 (1,25(OH)2D3) is critical for regulation of serum calcium and phosphorus levels and for proper maintenance of bone mineralization and neuromuscular function. Biological...
5.
Becklund B, James B, Gagel R, Deluca H
Arch Biochem Biophys . 2009 Jul; 488(2):105-8. PMID: 19563774
The active form of vitamin D, 1alpha,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)), can suppress disease in the experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis. Calcium appears to be a critical component of...
6.
Becklund B, Hansen Jr D, Deluca H
Proc Natl Acad Sci U S A . 2009 Mar; 106(13):5276-81. PMID: 19282478
The active form of vitamin D, 1alpha,25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)], suppresses disease development in the experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis (MS). However, complete disease prevention only occurs with...
7.
Boulware M, Weick J, Becklund B, Kuo S, Groth R, Mermelstein P
J Neurosci . 2005 May; 25(20):5066-78. PMID: 15901789
In addition to mediating sexual maturation and reproduction through stimulation of classical intracellular receptors that bind DNA and regulate gene expression, estradiol is also thought to influence various brain functions...