Bryan J Maloney
Overview
Explore the profile of Bryan J Maloney including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
62
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Recent Articles
1.
Rodgers L, Maloney B, Hartz A, Bauer B
Cancers (Basel)
. 2025 Mar;
17(5).
PMID: 40075583
: Most preclinical studies on glioblastoma (GBM) fail to provide translational utility in the clinic. Fluorescence-guided surgery using 5-aminolevulinic acid (5-ALA) improves tumor resection, disease prognosis, and, thus, patient outcomes....
2.
Nehra G, Maloney B, Smith R, Chumboatong W, Abner E, Nelson P, et al.
Fluids Barriers CNS
. 2025 Jan;
22(1):4.
PMID: 39789614
Background: Blood-brain barrier dysfunction is one characteristic of Alzheimer's disease (AD) and is recognized as both a cause and consequence of the pathological cascade leading to cognitive decline. The goal...
3.
Rodgers L, Schulz Pauly J, Maloney B, Hartz A, Bauer B
Cancers (Basel)
. 2024 Jun;
16(11).
PMID: 38893116
Glioblastoma (GBM) is the most aggressive brain cancer. To model GBM in research, orthotopic brain tumor models, including syngeneic models like GL261 and genetically engineered mouse models like TRP, are...
4.
Nehra G, Promsan S, Yubolphan R, Chumboatong W, Vivithanaporn P, Maloney B, et al.
Fluids Barriers CNS
. 2024 Mar;
21(1):29.
PMID: 38532486
Background: Patients with Alzheimer's disease (AD) develop blood-brain barrier dysfunction to varying degrees. How aging impacts Aβ pathology, blood-brain barrier function, and cognitive decline in AD remains largely unknown. In...
5.
Vulin M, Zhong Y, Maloney B, Bauer B, Hartz A
Fluids Barriers CNS
. 2023 Oct;
20(1):70.
PMID: 37803468
Background: Loss of P-glycoprotein (P-gp) at the blood-brain barrier contributes to amyloid-β (Aβ) brain accumulation in Alzheimer's disease (AD). Using transgenic human amyloid precursor protein (hAPP)-overexpressing mice (Tg2576), we previously...
6.
Maloney B, Takeda N, Suzaki Y, Ami Y, Li T, Miyamura T, et al.
Vaccine
. 2005 Mar;
23(15):1870-4.
PMID: 15734058
Recombinant hepatitis E virus capsid protein (HEV CP) assembles orally immunogenic virus-like particles (VLP) when expressed in an insect cell system. We used plant expression cassettes, pHEV101 and pHEV110, for...
7.
Huang Z, Elkin G, Maloney B, Beuhner N, Arntzen C, Thanavala Y, et al.
Vaccine
. 2005 Mar;
23(15):1851-8.
PMID: 15734055
Expression of vaccine antigens in plants and delivery via ingestion of transgenic plant material has shown promise in numerous pre-clinical animal studies and in a few clinical trials. A number...