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Bruno Jose Dumet Fernandes

Explore the profile of Bruno Jose Dumet Fernandes including associated specialties, affiliations and a list of published articles. Areas
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Citations 45
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Recent Articles
1.
Bidu N, Costa S, Couto R, Fernandes B
Curr Drug Saf . 2024 Sep; PMID: 39234907
Background: Ciprofloxacin is a fluoroquinolone antibiotic widely used in clinical practice with a fluorine atom in its chemical structure. Like other antibiotics, it can induce several adverse effects, such as...
2.
Bidu N, Lemos D, Fernandes B
Toxicol Ind Health . 2024 Sep; 40(12):637-642. PMID: 39222320
Arsenic and its inorganic compounds affect numerous organs and systemic functions, such as the nervous and hematopoietic systems, liver, kidneys, and skin. Despite a large number of studies on arsenic...
3.
Bidu N, Mattoso R, de Oliveira Santos O, Alves I, Fernandes B, Couto R
Curr Drug Res Rev . 2023 Oct; 16(3):403-411. PMID: 37861009
Background: Acute rejection remains one of the main complications in the first months after transplantation and may influence long-term outcomes. Tacrolimus has proven its usefulness in solid organ transplants and...
4.
Couto R, Fernandes B
Curr Drug Res Rev . 2021 Jan; 13(2):86-89. PMID: 33504322
Naltrexone (NTX) is an opioid antagonist that inhibits cell proliferation in vivo when administered in low doses. Naltrexone in low doses can reduce tumor growth by interfering with cell signalling...
5.
Fernandes B, Couto R
Toxicol Ind Health . 2020 Nov; 36(12):937-939. PMID: 33155520
Glycidyl methacrylate (GMA; CAS no. 106-91-2) is a chemical monomer used in the manufacture of dental resins, can coatings and polymers. GMA has demonstrated toxicity to the ocular, digestive, respiratory...
6.
Lima R, Ferreira M, de Jesus Ponte Carvalho T, Fernandes B, Takayanagui O, Garcia H, et al.
Br J Clin Pharmacol . 2011 Mar; 71(4):528-35. PMID: 21395645
Aim: This study investigated the kinetic disposition, metabolism and enantioselectivity of albendazole (ABZ) and praziquantel (PZQ) administered alone and in combination to healthy volunteers. Methods: A randomized crossover study was...
7.
Fernandes B, De Miranda Silva C, Andrade J, Matthes A, Coelho E, Lanchote V
Cancer Chemother Pharmacol . 2011 Feb; 68(4):897-904. PMID: 21290248
Purpose: Adjuvant chemotherapy with cyclophosphamide (CYC) is used for the treatment of breast cancer. CYC is used as a racemic mixture, although preclinical data have demonstrated differences in the efficacy...
8.
De Miranda Silva C, Fernandes B, Donadi E, Silva L, Coelho E, Dantas M, et al.
J Clin Pharmacol . 2009 Jun; 49(8):965-72. PMID: 19546252
The pharmacokinetics of cyclophosphamide (CYC) enantiomers were evaluated in patients with lupus nephritis distributed in 2 groups according to creatinine clearance: group 1 (90.6-144.6 mL/min/1.73 m(2)) and group 2 (42.8-76.4...
9.
De Miranda Silva C, Fernandes B, Marques Pereira M, Silva L, Donadi E, Matthes A, et al.
Chirality . 2008 Jun; 21(3):383-9. PMID: 18570312
This article describes the enantioselective analysis of cyclophosphamide (CPA) in human plasma using LC-MS/MS. CPA enantiomers were extracted from plasma using a mixture of ethyl acetate and chloroform (75:25, v/v)....
10.
Bonato P, de Oliveira A, Malagueno de Santana F, Fernandes B, Lanchote V, Gonzalez A, et al.
J Pharm Biomed Anal . 2006 Dec; 44(2):558-63. PMID: 17169522
The analysis of albendazole sulfoxide, albendazole sulfone, praziquantel and trans-4-hydroxypraziquantel in plasma was carried out by high-performance liquid chromatography-mass spectrometry ((LC-MS-MS). The plasma samples were prepared by liquid-liquid extraction using...