Brunda Nijagal
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Explore the profile of Brunda Nijagal including associated specialties, affiliations and a list of published articles.
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26
Citations
326
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Recent Articles
1.
Luo J, Frank D, Peterson A, Nijagal B, Arcot J
Food Chem X
. 2025 Mar;
26:102284.
PMID: 40083856
In this study volatile and non-volatile flavour metabolites were systematically measured in prawn, scallop, squid, barramundi, salmon, snapper, and tuna using headspace solid-phase microextraction gas chromatography-mass spectrometry for volatile compounds,...
2.
Wang X, Jowsey W, Cheung C, Smart C, Klaus H, Seeto N, et al.
Nat Commun
. 2024 Nov;
15(1):9791.
PMID: 39537607
Drug-resistant strains of Mycobacterium tuberculosis are a major global health problem. Resistance to the front-line antibiotic isoniazid is often associated with mutations in the katG-encoded bifunctional catalase-peroxidase. We hypothesise that...
3.
Windred D, Anderson C, Jeppe K, Ftouni S, Grant L, Nijagal B, et al.
Sci Rep
. 2024 Jul;
14(1):16796.
PMID: 39039133
Robust circadian rhythms are essential for optimal health. The central circadian clock controls temperature rhythms, which are known to organize the timing of peripheral circadian rhythms in rodents. In humans,...
4.
Bartho L, McKeating D, Walker S, Nijagal B, MacDonald T, Pritchard N, et al.
Sci Rep
. 2024 Jul;
14(1):15829.
PMID: 38982217
Metabolomics is the study of small molecules (metabolites), within cells, tissues and biofluids. Maternal metabolites can provide important insight into the health and development of both mother and fetus throughout...
5.
Jeppe K, Ftouni S, Nijagal B, Grant L, Lockley S, Rajaratnam S, et al.
Sci Adv
. 2024 Mar;
10(10):eadj6834.
PMID: 38457492
Sleep deprivation enhances risk for serious injury and fatality on the roads and in workplaces. To facilitate future management of these risks through advanced detection, we developed and validated a...
6.
Class IIa HDACs inhibit cell death pathways and protect muscle integrity in response to lipotoxicity
Martin S, Connor T, Sanigorski A, McEwen K, Henstridge D, Nijagal B, et al.
Cell Death Dis
. 2023 Dec;
14(12):787.
PMID: 38040704
Lipotoxicity, the accumulation of lipids in non-adipose tissues, alters the metabolic transcriptome and mitochondrial metabolism in skeletal muscle. The mechanisms involved remain poorly understood. Here we show that lipotoxicity increased...
7.
Lu T, Freytag L, Narayana V, Moore Z, Oliver S, Valkovic A, et al.
Metabolites
. 2023 Nov;
13(11).
PMID: 37999235
Matrix-assisted laser desorption/ionization mass spectrometry imaging allows for the study of metabolic activity in the tumor microenvironment of brain cancers. The detectable metabolites within these tumors are contingent upon the...
8.
Bartho L, Keenan E, Walker S, MacDonald T, Nijagal B, Tong S, et al.
EBioMedicine
. 2023 Jul;
94:104704.
PMID: 37421807
Background: Lipids serve as multifunctional metabolites that have important implications for the pregnant mother and developing fetus. Abnormalities in lipids have emerged as potential risk factors for pregnancy diseases, such...
9.
Mu A, Klare W, Baines S, Ignatius Pang C, Guerillot R, Harbison-Price N, et al.
Nat Commun
. 2023 Mar;
14(1):1530.
PMID: 36934086
Even in the setting of optimal resuscitation in high-income countries severe sepsis and septic shock have a mortality of 20-40%, with antibiotic resistance dramatically increasing this mortality risk. To develop...
10.
Yasa J, Reed C, Bournazos A, Evesson F, Pang I, Graham M, et al.
Acta Neuropathol Commun
. 2023 Jan;
11(1):15.
PMID: 36653852
Dysferlin is a Ca-activated lipid binding protein implicated in muscle membrane repair. Recessive variants in DYSF result in dysferlinopathy, a progressive muscular dystrophy. We showed previously that calpain cleavage within...