Bruna Los
Overview
Explore the profile of Bruna Los including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
7
Citations
25
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Bassani Borges J, Oliveira V, Dagli-Hernandez C, Monteiro Ferreira G, Barbosa T, Marcal E, et al.
Gene
. 2023 May;
875:147501.
PMID: 37217153
Familial hypercholesterolemia (FH) is a monogenic disease characterized by high plasma low-density lipoprotein cholesterol (LDL-c) levels and increased risk of premature atherosclerotic cardiovascular disease. Mutations in FH-related genes account for...
2.
Ostwaldt F, Los B, Heyd F
Front Immunol
. 2022 Nov;
13:1030409.
PMID: 36439187
There are multiple regulatory layers that control intracellular trafficking and protein secretion, ranging from transcriptional to posttranslational mechanisms. Finely regulated trafficking and secretion is especially important for lymphocytes during activation...
3.
Los B, Monteiro Ferreira G, Bassani Borges J, Kronenberger T, Oliveira V, Dagli-Hernandez C, et al.
Gene
. 2022 Oct;
851:146979.
PMID: 36261084
PCSK9 gain-of-function (GOF) variants increase degradation of low-density lipoprotein receptor (LDLR) and are potentially associated with Familial Hypercholesterolemia (FH). This study aimed to explore the effects of PCSK9 missense variants...
4.
Los B, Preussner M, Eschke K, Vidal R, Abdelgawad A, Olofsson D, et al.
Nucleic Acids Res
. 2022 Jun;
50(12):6769-6785.
PMID: 35713540
Antiviral innate immunity represents the first defense against invading viruses and is key to control viral infections, including SARS-CoV-2. Body temperature is an omnipresent variable but was neglected when addressing...
5.
Los B, Borges J, Oliveira V, Freitas R, Dagli-Hernandez C, Bortolin R, et al.
Epigenomics
. 2021 Apr;
13(10):779-791.
PMID: 33899508
Functional analysis of 3'UTR variants and mRNA-miRNA interactions were explored in patients with familial hypercholesterolemia (FH). 3'UTR variants were identified by exon-targeted gene sequencing. Functional effects of 3'UTR variants and...
6.
Dagli-Hernandez C, Freitas R, Marcal E, Goncalves R, Faludi A, Bassani Borges J, et al.
Ann Transl Med
. 2021 Feb;
9(1):76.
PMID: 33553369
Statins are the most widely used cholesterol-lowering drugs for cardiovascular diseases prevention. However, some patients are refractory to treatment, whereas others experience statin-related adverse events (SRAE). It has been increasingly...
7.
Bassani Borges J, Oliveira V, Monteiro Ferreira G, Los B, Barbosa T, Marcal E, et al.
Res Social Adm Pharm
. 2020 Nov;
17(7):1347-1355.
PMID: 33129683
Background: Familial hypercholesterolemia (FH) is a genetic disease that affects millions of people worldwide. Objectives: The study protocol FHBGEP was design to investigate the main genomic, epigenomic, and pharmacogenomic factors...