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Bruce W Surber

Explore the profile of Bruce W Surber including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 158
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Recent Articles
1.
Soli E, Surber B, Reed A
J Labelled Comp Radiopharm . 2021 Mar; 64(7):254-261. PMID: 33675109
Gonadotropin-releasing hormone (GnRH) receptor antagonists are an important class of compounds designed to block the pituitary gland from synthesizing follicle-stimulating hormone and luteinizing hormone for the treatment of sex hormone...
2.
Liu X, Shi Y, Maag D, Palma J, Patterson M, Ellis P, et al.
Clin Cancer Res . 2011 Dec; 18(2):510-23. PMID: 22128301
Purpose: PARP inhibitors are being developed as therapeutic agents for cancer. More than six compounds have entered clinical trials. The majority of these compounds are β-nicotinamide adenine dinucleotide (NAD(+))-competitive inhibitors....
3.
Chin C, Pauly J, Surber B, Skoubis P, McGaraughty S, Hradil V, et al.
Synapse . 2007 Dec; 62(3):159-68. PMID: 18081183
Neuronal nicotinic receptors are the subject of intensive research focused on developing novel therapies for drug abuse, neurocognitive disorders, neurodegenerative diseases, and pain. In this study, we have applied pharmacological...
4.
Witte D, Yao B, Miller T, Carr T, Cassar S, Sharma R, et al.
Br J Pharmacol . 2006 May; 148(5):657-70. PMID: 16715122
1. A-349821 is a selective histamine H3 receptor antagonist/inverse agonist. Herein, binding of the novel non-imidazole H3 receptor radioligand [3H]A-349821 to membranes expressing native or recombinant H3 receptors from rat...
5.
Haviv F, Bradley M, Kalvin D, Schneider A, Davidson D, Majest S, et al.
J Med Chem . 2005 Apr; 48(8):2838-46. PMID: 15828822
The heptapeptide 1, NAc-Gly-Val-DIle-Thr-Arg-Ile-ArgNHEt, a structurally modified fragment derived from the second type-1 repeat of thrombospondin-1 (TSP-1), is known to possess antiangiogenic activity. However, therapeutic utility could not be demonstrated...
6.
Moreland R, Terranova M, Chang R, Uchic M, Matulenko M, Surber B, et al.
Eur J Pharmacol . 2004 Aug; 497(2):147-54. PMID: 15306199
Tritiation of the dopamine D(4) receptor selective agonist A-369508 ([2-[4-(2-cyanophenyl)-1-piperazinyl]-N-(3-methylphenyl) acetamide) has provided a radioligand for the characterization of dopamine D(4) receptors. [(3)H] A-369508 binds with high affinity to the...