Brooke T Mossman
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Explore the profile of Brooke T Mossman including associated specialties, affiliations and a list of published articles.
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92
Citations
3968
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Recent Articles
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2.
Mossman B
Toxicol Appl Pharmacol
. 2018 Jul;
361:62-67.
PMID: 30030095
In vitro studies using target and effecter cells of mineral-induced cancers have been critical in determining the mechanisms of pathogenesis as well as the properties of elongated mineral particles (EMPs)...
3.
Perkins T, Peeters P, Albrecht C, Schins R, Dentener M, Mossman B, et al.
Toxicol Appl Pharmacol
. 2018 Apr;
348:43-53.
PMID: 29673857
Lung epithelial cells are the first cell-type to come in contact with hazardous dust materials. Upon deposition, they invoke complex reactions in attempt to eradicate particles from the airways, and...
4.
Traviss N, Li M, Lombard M, Thelen B, Palmer B, Poynter M, et al.
Air Qual Atmos Health
. 2018 Feb;
7(1):59-70.
PMID: 29430261
Diesel engine emissions are an important source of ultrafine particulate matter (PM) in both ambient air and many occupational settings. Biodiesel is a popular, 'green' alternative to petroleum diesel fuel,...
5.
Sayan M, Mossman B
Part Fibre Toxicol
. 2016 Sep;
13(1):51.
PMID: 27650313
The concept of the inflammasome, a macromolecular complex sensing cell stress or danger signals and initiating inflammation, was first introduced approximately a decade ago. Priming and activation of these intracellular...
6.
Perkins T, Dentener M, Stassen F, Rohde G, Mossman B, Wouters E, et al.
Toxicol Appl Pharmacol
. 2016 Apr;
301:61-70.
PMID: 27095093
Growth and development of the mature lung is a complex process orchestrated by a number of intricate developmental signaling pathways. Wingless-type MMTV-integration site (WNT) signaling plays critical roles in controlling...
7.
Kadariya Y, Menges C, Talarchek J, Cai K, Klein-Szanto A, Pietrofesa R, et al.
Cancer Prev Res (Phila)
. 2016 Mar;
9(5):406-414.
PMID: 26935421
Exposure to asbestos is causally associated with the development of malignant mesothelioma, a cancer of cells lining the internal body cavities. Malignant mesothelioma is an aggressive cancer resistant to all...
8.
Perkins T, Peeters P, Shukla A, Arijs I, Dragon J, Wouters E, et al.
Hum Mol Genet
. 2014 Oct;
24(5):1374-89.
PMID: 25351596
Occupational and environmental exposures to airborne asbestos and silica are associated with the development of lung fibrosis in the forms of asbestosis and silicosis, respectively. However, both diseases display distinct...
9.
Sayan M, Shukla A, MacPherson M, Macura S, Hillegass J, Perkins T, et al.
Am J Respir Cell Mol Biol
. 2014 Jun;
51(5):595-603.
PMID: 24940987
Malignant mesothelioma (MM), lung cancers, and asbestosis are hyperproliferative diseases associated with exposures to asbestos. All have a poor prognosis; thus, the need to develop novel and effective therapies is...
10.
Thompson J, Westbom C, MacPherson M, Mossman B, Heintz N, Spiess P, et al.
Part Fibre Toxicol
. 2014 Jun;
11:24.
PMID: 24885895
Background: Asbestos exposure is related to various diseases including asbestosis and malignant mesothelioma (MM). Among the pathogenic mechanisms proposed by which asbestos can cause diseases involving epithelial and mesothelial cells,...