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Brock Reeve

Explore the profile of Brock Reeve including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 397
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Recent Articles
1.
Bhere D, Choi S, van de Donk P, Hope D, Gortzak K, Kunnummal A, et al.
Nat Commun . 2022 May; 13(1):2810. PMID: 35589724
Cellular therapies offer a promising therapeutic strategy for the highly malignant brain tumor, glioblastoma (GBM). However, their clinical translation is limited by the lack of effective target identification and stringent...
2.
Levy O, Kuai R, Siren E, Bhere D, Milton Y, Nissar N, et al.
Sci Adv . 2020 Aug; 6(30):eaba6884. PMID: 32832666
More than 1050 clinical trials are registered at FDA.gov that explore multipotent mesenchymal stromal cells (MSCs) for nearly every clinical application imaginable, including neurodegenerative and cardiac disorders, perianal fistulas, graft-versus-host...
3.
Ng K, Smith J, McAteer M, Mead B, Ware J, Jackson F, et al.
Biotechnol Bioeng . 2018 Aug; 116(2):307-319. PMID: 30063243
Newly recognized as natural nanocarriers that deliver biological information between cells, extracellular vesicles (EVs), including exosomes and microvesicles, provide unprecedented therapeutic opportunities. Large-scale and cost-effective manufacturing is imperative for EV...
4.
Davies B, Smith J, Rikabi S, Wartolowska K, Morrey M, French A, et al.
J Tissue Eng . 2017 Aug; 8:2041731417724413. PMID: 28835816
Cellular therapies, such as stem cell-based treatments, have been widely researched and numerous products and treatments have been developed. Despite this, there has been relatively limited use of these technologies...
5.
Pettitt D, Arshad Z, Davies B, Smith J, French A, Cole D, et al.
Syst Rev . 2017 Jun; 6(1):120. PMID: 28651620
Background: Cellular-based therapies represent a platform technology within the rapidly expanding field of regenerative medicine and are distinct from conventional therapeutics-offering a unique approach to managing what were once considered...
6.
Caplan A, Mason C, Reeve B
Stem Cells Transl Med . 2017 Feb; 6(1):17-21. PMID: 28170173
The 3Rs for a good education are "reading, 'riting, and 'rithmetic." The basis for good health care solutions for the emergent field of cell therapy in the future will also...
7.
French A, Bravery C, Smith J, Chandra A, Archibald P, Gold J, et al.
Stem Cells Transl Med . 2015 Feb; 4(3):217-23. PMID: 25650438
There is a need for physical standards (reference materials) to ensure both reproducibility and consistency in the production of somatic cell types from human pluripotent stem cell (hPSC) sources. We...
8.
Silva M, Daheron L, Hurley H, Bure K, Barker R, Carr A, et al.
Cell Stem Cell . 2015 Jan; 16(1):13-7. PMID: 25575079
Induced pluripotent stem cells (iPSCs) have the potential to transform drug discovery and healthcare in the 21(st) century. However, successful commercialization will require standardized manufacturing platforms. Here we highlight the...
9.
Davies B, Rikabi S, French A, Pinedo-Villanueva R, Morrey M, Wartolowska K, et al.
J Tissue Eng . 2014 Nov; 5:2041731414551764. PMID: 25383173
There has been a large increase in basic science activity in cell therapy and a growing portfolio of cell therapy trials. However, the number of industry products available for widespread...
10.
French A, Suh J, Suh C, Rubin L, Barker R, Bure K, et al.
Trends Biotechnol . 2014 Aug; 32(9):436-40. PMID: 25150363
The approach to research and development in biomedical science is changing. Increasingly, academia and industry seek to collaborate, and share resources and expertise, by establishing partnerships. Here, we explore the...