Britton R Barbee
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Explore the profile of Britton R Barbee including associated specialties, affiliations and a list of published articles.
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6
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57
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Recent Articles
1.
Barbee B, Gourley S
Addict Neurosci
. 2023 Jul;
2.
PMID: 37485439
Cocaine use disorder (CUD) is a significant public health issue that generates substantial personal, familial, and economic burdens. Still, there are no FDA-approved pharmacotherapies for CUD. Cocaine-dependent individuals report anxiety...
2.
Davies R, Barbee B, Garcia-Sifuentes Y, Butkovich L, Gourley S
Neurobiol Learn Mem
. 2023 Jun;
203:107789.
PMID: 37328026
PI3-kinase (PI3K) is an intracellular signaling complex that is stimulated upon cocaine exposure and linked with the behavioral consequences of cocaine. We recently genetically silenced the PI3K p110β subunit in...
3.
Li D, Dighe N, Barbee B, Pitts E, Kochoian B, Blumenthal S, et al.
Nat Neurosci
. 2022 Aug;
25(9):1213-1224.
PMID: 36042313
Behavioral flexibility-that is, the ability to deviate from established behavioral sequences-is critical for navigating dynamic environments and requires the durable encoding and retrieval of new memories to guide future choice....
4.
Shapiro L, Pitts E, Li D, Barbee B, Hinton E, Bassell G, et al.
Biol Psychiatry
. 2021 Mar;
89(10):959-969.
PMID: 33773752
Background: The PI3-kinase (PI3K) complex is a well-validated target for mitigating cocaine-elicited sequelae, but pan-PI3K inhibitors are not viable long-term treatment options. The PI3K complex is composed of p110 catalytic...
5.
Woon E, Sequeira M, Barbee B, Gourley S
J Neurosci Res
. 2019 Dec;
98(6):1020-1030.
PMID: 31820488
Goal-directed action refers to selecting behaviors based on the expectation that they will be reinforced with desirable outcomes. It is typically conceptualized as opposing habit-based behaviors, which are instead supported...
6.
Whyte A, Kietzman H, Swanson A, Butkovich L, Barbee B, Bassell G, et al.
J Neurosci
. 2019 Apr;
39(23):4595-4605.
PMID: 30940719
An essential aspect of goal-directed decision-making is selecting actions based on anticipated consequences, a process that involves the orbitofrontal cortex (OFC) and potentially, the plasticity of dendritic spines in this...