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Brile Chung

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Articles 9
Citations 279
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Recent Articles
1.
Chung B, Esmaeili A, Gopalakrishna-Pillai S, Murad J, Andersen E, Reddy N, et al.
NPJ Breast Cancer . 2017 Jun; 3:6. PMID: 28649646
The tumor microenvironment is composed of heterogeneous populations of cells, including cancer, immune, and stromal cells. Progression of tumor growth and initiation of metastasis is critically dependent on the reciprocal...
2.
Chung B, Stuge T, Murad J, Beilhack G, Andersen E, Armstrong B, et al.
Cell Rep . 2014 Aug; 8(3):871-882. PMID: 25088413
Current vaccine conditions predominantly elicit low-avidity cytotoxic T lymphocytes (CTLs), which are non-tumor-cytolytic but indistinguishable by tetramer staining or enzyme-linked immunospot from high-avidity CTLs. Using CTL clones of high or...
3.
Chung B, Montel-Hagen A, Ge S, Blumberg G, Kim K, Klein S, et al.
Stem Cells . 2014 May; 32(9):2386-96. PMID: 24801626
A system that allows manipulation of the human thymic microenvironment is needed both to elucidate the extrinsic mechanisms that control human thymopoiesis and to develop potential cell therapies for thymic...
4.
Huang G, Pashmforoush M, Chung B, Saxon L
J Cardiovasc Transl Res . 2010 Dec; 4(1):61-5. PMID: 21128127
Recent advances in stem cell biology and tissue engineering have put forth new therapeutic paradigms for treatment of myocardial disease. The aim of stem cell therapy for myocardial regeneration has...
5.
Chung B, Min D, Joo L, Krampf M, Huang J, Yang Y, et al.
Biol Blood Marrow Transplant . 2010 Aug; 17(1):48-60. PMID: 20713165
The decreased ability of the thymus to generate T cells after bone marrow transplantation (BMT) is a clinically significant problem. Interleukin (IL)-7 and stem cell factor (SCF) induce proliferation, differentiation,...
6.
Ren Y, Graf Finckenstein F, Abdueva D, Shahbazian V, Chung B, Weinberg K, et al.
Cancer Res . 2008 Aug; 68(16):6587-97. PMID: 18701482
Alveolar rhabdomyosarcomas (ARMS) are highly malignant soft-tissue sarcomas that arise in children, adolescents, and young adults. Although formation and expression of the PAX-FKHR fusion genes is thought to be the...
7.
Chung B, Dudl E, Toyama A, Barsky L, Weinberg K
Biol Blood Marrow Transplant . 2007 Dec; 14(1):16-27. PMID: 18158957
Interleukin (IL)-7 promotes both thymopoiesis and mature T lymphocyte survival and proliferation in experimental murine models of hematopoietic stem cell (HSC) transplantation. Because HSC products for transplantation also may contain...
8.
Chung B, Dudl E, Min D, Barsky L, Smiley N, Weinberg K
Blood . 2007 Jun; 110(8):2803-10. PMID: 17595335
Graft-versus-host disease (GVHD) continues to be a serious complication that limits the success of allogeneic bone marrow transplantation (BMT). Using IL-7-deficient murine models, we have previously shown that IL-7 is...
9.
Min D, Taylor P, Panoskaltsis-Mortari A, Chung B, Danilenko D, Farrell C, et al.
Blood . 2002 May; 99(12):4592-600. PMID: 12036893
Decreased thymopoietic capacity contributes to the severe and clinically significant immune deficiency seen after bone marrow transplantation (BMT). One mechanism for thymopoietic failure is damage to the interleukin 7 (IL-7)-producing...