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Brian S Ko

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Articles 48
Citations 1270
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Recent Articles
1.
Pradhan R, Chimene D, Ko B, Goncharov A, Ozcan A, McShane M
ACS Sens . 2024 Nov; 9(11):6060-6070. PMID: 39494514
Chronic diseases, including diabetes, cardiovascular diseases, and microvascular complications, contribute significantly to global morbidity and mortality. Current monitoring tools such as glucometers and continuous glucose monitors only measure one analyte;...
2.
Ihdayhid A, Sehly A, He A, Joyner J, Flack J, Konstantopoulos J, et al.
JACC Adv . 2024 Oct; 3(9):100861. PMID: 39372456
Background: Coronary computed tomography angiography (CCTA) has emerged as a reliable noninvasive modality to assess coronary artery stenosis and high-risk plaque (HRP). However, CCTA assessment of stenosis and HRP is...
3.
Chimene D, Queener K, Ko B, McShane M, Daniele M
Annu Rev Biomed Eng . 2024 Feb; 26(1):197-221. PMID: 38346276
Insertable biosensor systems are medical diagnostic devices with two primary components: an implantable biosensor within the body and a wearable monitor that can remotely interrogate the biosensor from outside the...
4.
Dong P, Singh K, Soltes A, Ko B, Gaharwar A, McShane M, et al.
J Mater Chem B . 2022 Aug; 10(32):6118-6132. PMID: 35916077
Glucose biosensors that could be subcutaneously injected and interrogated without a physically connected electrode and transmitter affixed to skin would represent a major advancement in reducing the user burden of...
5.
Chua A, Ihdayhid A, Linde J, Sorgaard M, Cameron J, Seneviratne S, et al.
Heart Lung Circ . 2022 May; 31(8):1102-1109. PMID: 35501246
Background: Non-invasive computed tomography (CT)-derived fractional flow reserve (FFR) is computed from standard coronary CT angiography (CTA) datasets and provides accurate vessel-specific ischaemia assessment of coronary artery disease (CAD). To...
6.
Dong P, Ko B, Lomeli K, Clark E, McShane M, Grunlan M
Macromol Rapid Commun . 2022 Mar; 43(9):e2100902. PMID: 35253953
The adoption of existing continuous glucose monitors (CGMs) is limited by user burden. Herein, a design for a glucose biosensor with the potential for subcutaneous implantation, without the need for...
7.
Leong P, Osadnik C, King P, MacDonald M, Ko B, Lau K, et al.
Respirology . 2021 Oct; 27(1):56-65. PMID: 34693587
Background And Objective: Right ventricular (RV) volumes are crucial outcome determinants in pulmonary diseases. Little is known about the associations of RV volumes during hospitalized acute exacerbations of chronic obstructive...
8.
Riedl K, Jensen J, Ko B, Leipsic J, Grove E, Mathiassen O, et al.
Int J Cardiovasc Imaging . 2021 Aug; 37(11):3299-3308. PMID: 34383150
The presence of left main coronary artery disease (LMCAD) is associated with an unfavorable clinical outcome. The clinical utility of FFR testing for non-invasive physiological assessment in LMCAD remains largely...
9.
Pavlin-Premrl D, Boopathy S, Nemes A, Mohammadzadeh M, Monajemi S, Ko B, et al.
J Stroke Cerebrovasc Dis . 2021 Aug; 30(10):106009. PMID: 34343837
Background: Intracranial atherosclerosis is a common cause of stroke with a high recurrence rate. Haemodynamically significant lesions are associated with a particularly high risk of recurrence. Computational fluid dynamics (CFD)...
10.
Leong P, MacDonald M, King P, Osadnik C, Ko B, Landry S, et al.
ERJ Open Res . 2021 Jun; 7(1). PMID: 34104641
Introduction: Acute exacerbations of COPD (AECOPD) are accompanied by escalations in cardiac risk superimposed upon elevated baseline risk. Appropriate treatment for coronary artery disease (CAD) and heart failure with reduced...