Brian P Lazzaro
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Explore the profile of Brian P Lazzaro including associated specialties, affiliations and a list of published articles.
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85
Citations
4250
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Recent Articles
1.
Adhikari K, Lazzaro B
Biol Lett
. 2025 Feb;
21(2):20240475.
PMID: 39965650
Trade-offs occur when an organism has to allocate limited resources to multiple biological processes. How organisms allocate their resources and whether one trait gets priority over another is poorly understood....
2.
Darby A, Keith S, Kalukin A, Lazzaro B
J Exp Biol
. 2025 Jan;
228(1).
PMID: 39801480
Bacterial infections can substantially impact host metabolic health as a result of the direct and indirect demands of sustaining an immune response and of nutrient piracy by the pathogen itself....
3.
Darby A, Okoro D, Aredas S, Frank A, Pearson W, Dionne M, et al.
PLoS Pathog
. 2024 Aug;
20(8):e1012447.
PMID: 39133760
Overnutrition with dietary sugar can worsen infection outcomes in diverse organisms including insects and humans, through generally unknown mechanisms. In the present study, we show that adult Drosophila melanogaster fed...
4.
Darby A, Lazzaro B
Front Immunol
. 2024 Apr;
15:1400514.
PMID: 38576609
[This corrects the article DOI: 10.3389/fimmu.2023.1276357.].
5.
Stone E, Durkin E, Cook A, Richardson E, Lazzaro B, Keiser C
J Invertebr Pathol
. 2024 Mar;
204:108084.
PMID: 38452853
Opportunistic bacterial infections are common in insect populations but there is little information on how they are acquired or transmitted. We tested the hypothesis that Macrocheles mites can transmit systemic...
6.
Interactions between innate immunity and insulin signaling affect resistance to infection in insects
Darby A, Lazzaro B
Front Immunol
. 2023 Nov;
14:1276357.
PMID: 37915572
An active immune response is energetically demanding and requires reallocation of nutrients to support resistance to and tolerance of infection. Insulin signaling is a critical global regulator of metabolism and...
7.
Rombaut A, Gallet R, Qitout K, Samy M, Guilhot R, Ghirardini P, et al.
Microbiome
. 2023 Sep;
11(1):201.
PMID: 37679800
Background: The influence of microbiota in ecological interactions, and in particular competition, is poorly known. We studied competition between two insect species, the invasive pest Drosophila suzukii and the model...
8.
Hollingsworth B, Grubaugh N, Lazzaro B, Murdock C
PLoS Pathog
. 2023 Aug;
19(8):e1011588.
PMID: 37651317
Several aspects of mosquito ecology that are important for vectored disease transmission and control have been difficult to measure at epidemiologically important scales in the field. In particular, the ability...
9.
Radhika R, Lazzaro B
PLoS One
. 2023 Jul;
18(7):e0288342.
PMID: 37440541
Most organisms are under constant and repeated exposure to pathogens, leading to perpetual natural selection for more effective ways to fight-off infections. This could include the evolution of memory-based immunity...
10.
Radhika R, Lazzaro B
bioRxiv
. 2023 May;
PMID: 37163106
Most organisms are under constant and repeated exposure to pathogens, leading to perpetual natural selection for more effective ways to fight-off infections. This could include the evolution of memory-based immunity...