Brian Ortmann
Overview
Explore the profile of Brian Ortmann including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
145
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Recent Articles
1.
Porter L, Guo W, Crozier T, Greenwood E, Ortmann B, Kottmann D, et al.
Heliyon
. 2023 Mar;
9(3):e14383.
PMID: 36938474
Cigarette smoking has many serious negative health consequences. The relationship between smoking and SARS-CoV-2 infection is controversial, specifically whether smokers are at increased risk of infection. We investigated the impact...
2.
Ono M, Yamada K, Bensaddek D, Afzal V, Biddlestone J, Ortmann B, et al.
PLoS One
. 2016 Apr;
11(4):e0154759.
PMID: 27128805
The snoMEN (snoRNA Modulator of gene ExpressioN) vector technology was developed from a human box C/D snoRNA, HBII-180C, which contains an internal sequence that can be manipulated to make it...
3.
Ortmann B, Bensaddek D, Carvalhal S, Moser S, Mudie S, Griffis E, et al.
J Cell Sci
. 2015 Dec;
129(1):191-205.
PMID: 26644182
PHD1 (also known as EGLN2) belongs to a family of prolyl hydroxylases (PHDs) that are involved in the control of the cellular response to hypoxia. PHD1 is also able to...
4.
Mudie S, Bandarra D, Batie M, Biddlestone J, Moniz S, Ortmann B, et al.
Cell Cycle
. 2015 Jan;
13(24):3878-91.
PMID: 25558831
Hypoxia is an important developmental cue for multicellular organisms but it is also a contributing factor for several human pathologies, such as stroke, cardiovascular diseases and cancer. In cells, hypoxia...
5.
Ortmann B, Druker J, Rocha S
Cell Mol Life Sci
. 2014 May;
71(18):3569-82.
PMID: 24858415
Hypoxia' or decreases in oxygen availability' results in the activation of a number of different responses at both the whole organism and the cellular level. These responses include drastic changes...
6.
Sargent F, Davidson F, Kelly C, Binny R, Christodoulides N, Gibson D, et al.
Microbiology (Reading)
. 2013 Sep;
159(Pt 11):2427-2436.
PMID: 24014666
In general, prokaryotes are considered to be single-celled organisms that lack internal membrane-bound organelles. However, many bacteria produce proteinaceous microcompartments that serve a similar purpose, i.e. to concentrate specific enzymic...
7.
Moser S, Bensaddek D, Ortmann B, Maure J, Mudie S, Blow J, et al.
Dev Cell
. 2013 Aug;
26(4):381-92.
PMID: 23932902
PHD1 belongs to the family of prolyl-4-hydroxylases (PHDs) that is responsible for posttranslational modification of prolines on specific target proteins. Because PHD activity is sensitive to oxygen levels and certain...