Brian N Tse
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Explore the profile of Brian N Tse including associated specialties, affiliations and a list of published articles.
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5
Citations
195
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Recent Articles
1.
Tse B, Adalja A, Houchens C, Larsen J, Inglesby T, Hatchett R
Clin Infect Dis
. 2017 Oct;
65(3):495-500.
PMID: 28985671
Due to increasing rates of antimicrobial-resistant infections and the current inadequacy of the antibiotic pipeline, there is increasing interest in nontraditional approaches to antibacterial therapies. We define "traditional" agents as...
2.
Tse B, Snyder T, Shen Y, Liu D
J Am Chem Soc
. 2008 Oct;
130(46):15611-26.
PMID: 18956864
DNA-templated organic synthesis enables the translation, selection, and amplification of DNA sequences encoding synthetic small-molecule libraries. Previously we described the DNA-templated multistep synthesis and model in vitro selection of a...
3.
Snyder T, Tse B, Liu D
J Am Chem Soc
. 2008 Jan;
130(4):1392-401.
PMID: 18179216
DNA-templated organic synthesis enables the translation, selection, and amplification of DNA sequences encoding synthetic small-molecule libraries. As the size of DNA-templated libraries increases, the possibility of forming intramolecularly base-paired structures...
4.
Gartner Z, Tse B, Grubina R, Doyon J, Snyder T, Liu D
Science
. 2004 Aug;
305(5690):1601-5.
PMID: 15319493
The translation of nucleic acid libraries into corresponding synthetic compounds would enable selection and amplification principles to be applied to man-made molecules. We used multistep DNA-templated organic synthesis to translate...
5.
Li X, Gartner Z, Tse B, Liu D
J Am Chem Soc
. 2004 Apr;
126(16):5090-2.
PMID: 15099091
The translation of DNA into synthetic molecules enables their manipulation by powerful evolution-based methods previously available only to proteins and nucleic acids. The development of increasingly sophisticated DNA-templated small-molecule syntheses...