Brian Lichty
Overview
Explore the profile of Brian Lichty including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
249
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0
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Recent Articles
1.
Thatte A, DeWitte-Orr S, Lichty B, Mossman K, Ashkar A
Immunol Cell Biol
. 2011 Feb;
89(6):663-9.
PMID: 21339766
Innate antiviral immunity, particularly at mucosal surfaces, has a critical role in early control of viral infections. Both type I interferons (IFNs) and interleukin-15 (IL-15) are essential components of innate...
2.
Tomic J, Lichty B, Spaner D
Blood
. 2011 Jan;
117(9):2668-80.
PMID: 21205928
The type I interferons (IFNs) normally suppress tumor growth by phosphorylating and activating the signal transducer and activator of transcription 1 (STAT1), but also briefly activate STAT3, which promotes cell...
3.
Davies E, Reid S, Medina M, Lichty B, Ashkar A
J Leukoc Biol
. 2010 Jun;
88(3):529-36.
PMID: 20538758
The innate immune system is crucial for host defense and immunosurveillance against pathogens and tumor cells. IL-15 is a pleiotropic cytokine with important effects on cells of the innate and...
4.
Mossman K, Mian M, Lauzon N, Gyles C, Lichty B, MacKenzie R, et al.
J Immunol
. 2008 Nov;
181(10):6702-6.
PMID: 18981086
Several TLR ligands of bacterial origin induce innate immune responses. Although FimH, the adhesin portion of type 1 fimbria, plays an important role in the pathogenicity of some gram-negative bacteria,...
5.
Lun X, Senger D, Alain T, Oprea A, Parato K, Stojdl D, et al.
J Natl Cancer Inst
. 2006 Nov;
98(21):1546-57.
PMID: 17077357
Background: An ideal virus for the treatment of cancer should have effective delivery into multiple sites within the tumor, evade immune responses, produce rapid viral replication, spread within the tumor,...
6.
Gill N, Deacon P, Lichty B, Mossman K, Ashkar A
J Virol
. 2006 Sep;
80(20):9943-50.
PMID: 17005672
Toll-like receptors (TLRs) constitute a family of innate receptors that recognize and respond to a wide spectrum of microorganisms, including fungi, bacteria, viruses, and protozoa. Previous studies have demonstrated that...
7.
Bell J, Lichty B, Stojdl D
Cancer Cell
. 2003 Aug;
4(1):7-11.
PMID: 12892708
An international meeting was held on the development and application of replicating viruses for cancer therapy this past March in Banff, Alberta. In this review, using the presentations at this...