Brian H Clowers
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Explore the profile of Brian H Clowers including associated specialties, affiliations and a list of published articles.
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103
Citations
1790
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Recent Articles
1.
Smith C, Clowers B, Kregel S
J Am Soc Mass Spectrom
. 2025 Jan;
36(2):236-240.
PMID: 39834025
In this communication we report the construction of a printed circuit board which mounts directly to the vacuum chamber of a mass spectrometer and produces the RF waveforms needed by...
2.
Buzitis N, Clowers B
J Am Soc Mass Spectrom
. 2025 Jan;
36(2):424-432.
PMID: 39754593
Phased structures for lossless ion manipulation offer significant improvements over the scanning second gate method for coupling with ion trap mass analyzers. With an experimental run time of under 1...
3.
Butalewicz J, Sanders J, Juetten K, Buzitis N, Clowers B, Brodbelt J
Anal Chem
. 2024 Sep;
96(39):15674-15681.
PMID: 39283946
Owing to its ability to generate extensive fragmentation of proteins, ultraviolet photodissociation (UVPD) mass spectrometry (MS) has emerged as a versatile ion activation technique for the structural characterization of native...
4.
Yu Z, Huang M, Clowers B
Clin Mass Spectrom
. 2024 Aug;
10:16-24.
PMID: 39193356
Melanoma accounts for more than 60% of deaths associated with skin cancer, making its early detection through dermatological screening essential for improved treatment outcomes. Early detection and successful treatment of...
5.
Greer C, Kinlein Z, Clowers B
Rapid Commun Mass Spectrom
. 2024 Aug;
38(20):e9900.
PMID: 39185572
Rationale: TW-SLIM ion mobility separations have demonstrated exceptional resolution by leveraging long paths with minimal loss. All previously reported experiments have used electrode surfaces which are mirrored to generate symmetrically...
6.
Chakravorty S, Groetsema E, Obe F, Huntley A, Anderson G, Clowers B, et al.
J Am Soc Mass Spectrom
. 2024 Jul;
35(8):1702-1712.
PMID: 38995676
Recent improvements to the comparison-based method of digital waveform generation increased the reproducibility of the waveforms so that the higher-order Mathieu stability zones can be accessed reliably. Digitally driven quadrupole...
7.
Schramm H, Cabrera E, Greer C, Clowers B
J Am Soc Mass Spectrom
. 2024 Jul;
35(8):1883-1890.
PMID: 38994799
The latest iteration of modular, open-source rolled ion mobility spectrometers was characterized and tailored for heated ion chemistry experiments. Because the nature of ion-neutral interactions is innately linked to the...
8.
Kinlein Z, Clowers B
Anal Chem
. 2024 Apr;
96(16):6450-6458.
PMID: 38603648
With its capacity to store and translate ions across considerable distances and times, traveling wave structures for lossless ion manipulations (TW-SLIM) provide the foundation to expand the scope of ion...
9.
Buzitis N, Clowers B
J Am Soc Mass Spectrom
. 2024 Mar;
35(4):804-813.
PMID: 38512132
Toward the goal of minimizing construction costs while maintaining high performance, a new, reduced-pressure, drift tube ion mobility system is coupled with an ion trap mass analyzer through a custom...
10.
Cabrera E, Schrader R, Walker T, Laganowsky A, Russell D, Clowers B
Int J Mass Spectrom
. 2024 Feb;
497.
PMID: 38352886
Through optimization of terminal frequencies and effective sampling rates, we have developed nonlinear sawtooth-shaped frequency sweeps for efficient Fourier transform ion mobility mass spectrometry (FT-IM-MS) experiments. This is in contrast...