Brian G Jorgensen
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Explore the profile of Brian G Jorgensen including associated specialties, affiliations and a list of published articles.
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15
Citations
225
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Recent Articles
1.
Ha S, Singh R, Jin B, Baek G, Jorgensen B, Zogg H, et al.
Int J Mol Sci
. 2024 Sep;
25(18).
PMID: 39337631
Gender and biological sex have distinct impacts on the pathogenesis of type 2 diabetes (T2D). Estrogen deficiency is known to predispose female mice to T2D. In our previous study, we...
2.
Younis H, Ha S, Jorgensen B, Verma A, Ro S
J Pers Med
. 2022 Dec;
12(11).
PMID: 36573710
Maturity-Onset Diabetes of the Young (MODY) is a rare form of diabetes which affects between 1% and 5% of diagnosed diabetes cases. Clinical characterizations of MODY include onset of diabetes...
3.
Ha S, Jorgensen B, Wei L, Jin B, Kim M, Poudrier S, et al.
Int J Mol Sci
. 2022 May;
23(9).
PMID: 35563399
Metalloendopeptidase ADAM-Like Decysin 1 (ADAMDEC1) is an anti-inflammatory peptidase that is almost exclusively expressed in the gastrointestinal (GI) tract. We have recently found abundant and selective expression of Adamdec1 in...
4.
Ha S, Jin B, Jorgensen B, Zogg H, Wei L, Singh R, et al.
PLoS One
. 2022 May;
17(5):e0261743.
PMID: 35560163
Subepithelial platelet-derived growth factor receptor alpha (PDGFRα)+ cells found in the colonic mucosal tissue come in close contact with epithelial cells, immune cells, neurons, capillaries, and lymphatic networks. Mucosal subepithelial...
5.
Jorgensen B, Ro S
Int J Mol Sci
. 2022 Feb;
23(4).
PMID: 35216281
The gastrointestinal (GI) tract in mammals is comprised of dozens of cell types with varied functions, structures, and histological locations that respond in a myriad of ways to epigenetic and...
6.
Knupp D, Jorgensen B, Alshareef H, Bhat J, Grubbs J, Miura P, et al.
Aging Cell
. 2022 Feb;
21(2):e13560.
PMID: 35102684
Accumulation of circular RNAs (circRNAs) during aging occurs on a genome-wide level for multiple organisms, but its significance is unknown. Generating circRNA loss-of-function mutants is difficult because the vast majority...
7.
Wei L, Singh R, Ha S, Martin A, Jones L, Jin B, et al.
Gastroenterology
. 2021 Mar;
160(7):2451-2466.e19.
PMID: 33662386
Background & Aims: Gastrointestinal (GI) motility is regulated by serotonin (5-hydroxytryptamine [5-HT]), which is primarily produced by enterochromaffin (EC) cells in the GI tract. However, the precise roles of EC...
8.
Singh R, Ha S, Wei L, Jin B, Zogg H, Poudrier S, et al.
Gastroenterology
. 2021 Jan;
160(5):1662-1678.e18.
PMID: 33421511
Background & Aims: Interstitial cells of Cajal (ICCs) and pancreatic β cells require receptor tyrosine kinase (KIT) to develop and function properly. Degeneration of ICCs is linked to diabetic gastroparesis....
9.
Jorgensen B, Ro S
J Neurogastroenterol Motil
. 2019 Jul;
25(3):377-386.
PMID: 31327220
The mammalian intestine contains many different cell types but is comprised of 2 main cell types: epithelial cells and smooth muscle cells. Recent in vivo and in vitro evidence has...
10.
Breland A, Ha S, Jorgensen B, Jin B, Gardner T, Sanders K, et al.
Sci Rep
. 2019 Jan;
9(1):387.
PMID: 30674925
Transcriptome data on the quantitative numbers of transcriptional variants expressed in primary cells offer essential clues into specific cellular functions and biological processes. We have previously collected transcriptomes from primary...