Brian G Gazzard
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Explore the profile of Brian G Gazzard including associated specialties, affiliations and a list of published articles.
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48
Citations
1431
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Recent Articles
1.
Sullivan A, Saunders J, Desai M, Cartier A, Mitchell H, Jaffer S, et al.
Lancet HIV
. 2023 Dec;
10(12):e790-e806.
PMID: 38040478
Background: HIV pre-exposure prophylaxis (PrEP) is highly effective in preventing HIV acquisition. To enable routine commissioning of PrEP in England, we aimed to establish population need, duration of need, PrEP...
2.
Martin T, Martin N, Hickman M, Vickerman P, Page E, Everett R, et al.
AIDS
. 2013 Jun;
27(16):2551-7.
PMID: 23736152
Objective: Liver disease secondary to hepatitis C virus (HCV) infection in the context of HIV infection is one of the leading non-AIDS causes of death. Sexual transmission of HCV infection...
3.
Gregson J, Kuri-Cervantes L, Mela C, Gazzard B, Bower M, Goodier M
AIDS Res Hum Retroviruses
. 2012 Aug;
29(1):84-8.
PMID: 22920222
Chronic HIV-1 infection results in the expansion of both NKG2C+ and CD16+CD56- human natural killer cells. NKG2C+ cells proliferate in response to human cytomegalovirus (HCMV) and expansion of the dysfunctional...
4.
Paton N, Goodall R, Dunn D, Franzen S, Collaco-Moraes Y, Gazzard B, et al.
JAMA
. 2012 Jul;
308(4):353-61.
PMID: 22820788
Context: Therapies to decrease immune activation might be of benefit in slowing HIV disease progression. Objective: To determine whether hydroxychloroquine decreases immune activation and slows CD4 cell decline. Design, Setting,...
5.
Mandalia S, Westrop S, Beck E, Nelson M, Gazzard B, Imami N
PLoS One
. 2012 Feb;
7(2):e29844.
PMID: 22363409
Define and identify long-term non-progressors (LTNP) and HIV controllers (HIC), and estimate time until disease progression. LTNP are HIV-1(+) patients who maintain stable CD4(+) T-cell counts, with no history of...
6.
Clark S, Page E, Ford T, Metcalf R, Pozniak A, Nelson M, et al.
J Allergy Clin Immunol
. 2011 Jul;
128(4):838-846.e5.
PMID: 21745684
Background: In HIV-1-infected patients impaired IFN-γ responses to purified protein derivative (PPD) are associated with an increased risk of active tuberculosis. Tuberculosis antigen-specific cells are found in the T(H)1/T(H)17 subset...
7.
Waters L, Scourfield A, Marcano M, Gazzard B, Bower M, Nelson M, et al.
Clin Infect Dis
. 2011 Feb;
52(5):671-3.
PMID: 21292672
CCR5 antagonists may provide a well-tolerated switch option for patients experiencing tolerability or toxicity of their antiretroviral regimen. We analyzed stored samples from patients undergoing planned treatment interruptions for reasons...
8.
Ware L, Jackson A, Wootton S, Burdge G, Morlese J, Moyle G, et al.
Br J Nutr
. 2009 Jun;
102(7):1038-46.
PMID: 19480729
Mechanisms underlying the lipodystrophy syndrome associated with antiretroviral therapy (ART) for HIV infection are not completely understood. We investigated the effect of ART on blood lipid concentrations in the fasting...
9.
Annan N, Nelson M, Mandalia S, Bower M, Gazzard B, Stebbing J
J Acquir Immune Defic Syndr
. 2009 Apr;
51(2):140-6.
PMID: 19352201
Objectives: We wished to determine the efficacy of nonnucleoside reverse transcriptase inhibitor (NNRTI)-based regimens in antiretroviral-naive patients commencing highly active antiretroviral therapy (HAART) and to evaluate the effect of calendar...
10.
Gregson J, Steel A, Bower M, Gazzard B, Gotch F, Goodier M
AIDS
. 2008 Dec;
23(1):29-34.
PMID: 19050383
Background: Lipopolysaccharide (LPS) is elevated in the plasma of individuals chronically infected with HIV-1 and is thought to contribute to chronic immune activation of myeloid cells and T-cells. Natural killer...