Brian E Crucian
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Explore the profile of Brian E Crucian including associated specialties, affiliations and a list of published articles.
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45
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1585
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Recent Articles
1.
Crucian B, Quiriarte H, Lam C, Nelman M, Colorado A, Diak D, et al.
Front Immunol
. 2025 Feb;
16:1538421.
PMID: 39981230
Background: Due to cosmic radiation bombardment and over 4 billion meteorite and micrometeoroid impacts on the airless Moon, the lunar surface is covered by a layer of fine, reactive dust....
2.
Moreno-Villanueva M, Jimenez-Chavez L, Krieger S, Ding L, Zhang Y, Babiak-Vazquez A, et al.
Front Immunol
. 2025 Feb;
15:1512578.
PMID: 39902046
Introduction: The impact of spaceflight on the immune system and mitochondria has been investigated for decades. However, the molecular mechanisms underlying spaceflight-induced immune dysregulations are still unclear. Methods: In this...
3.
Diak D, Crucian B, Nelman-Gonzalez M, Mehta S
Viruses
. 2025 Jan;
16(12.
PMID: 39772216
Many biological markers of normal and disease states can be detected in saliva. The benefits of saliva collection for research include being non-invasive, ease of frequent sample collection, saving time,...
4.
Mehta S, Diak D, Bustos-Lopez S, Nelman-Gonzalez M, Chen X, Plante I, et al.
Int J Mol Sci
. 2024 Oct;
25(19).
PMID: 39408667
Human exploration of the solar system will expose crew members to galactic cosmic radiation (GCR), with a potential for adverse health effects. GCR particles (protons and ions) move at nearly...
5.
Kim J, Tierney B, Overbey E, Dantas E, Fuentealba M, Park J, et al.
Nat Commun
. 2024 Jun;
15(1):4954.
PMID: 38862516
Spaceflight induces an immune response in astronauts. To better characterize this effect, we generated single-cell, multi-ome, cell-free RNA (cfRNA), biochemical, and hematology data for the SpaceX Inspiration4 (I4) mission crew....
6.
Overbey E, Kim J, Tierney B, Park J, Houerbi N, Lucaci A, et al.
Nature
. 2024 Jun;
632(8027):1145-1154.
PMID: 38862028
Spaceflight induces molecular, cellular and physiological shifts in astronauts and poses myriad biomedical challenges to the human body, which are becoming increasingly relevant as more humans venture into space. Yet...
7.
Mehta S, Suresh R, Brandt K, Diak D, Smith S, Zwart S, et al.
J Allergy Clin Immunol Glob
. 2024 Apr;
3(2):100244.
PMID: 38577482
A case report detailing, for the first time, a case of laboratory-confirmed zoster in an astronaut on board the International Space Station is presented. The findings of reduced T-cell function,...
8.
Rea D, Miller R, Crucian B, Valentine R, Cristoforetti S, Bearg S, et al.
Nat Commun
. 2024 Mar;
15(1):2634.
PMID: 38528030
Real-time lab analysis is needed to support clinical decision making and research on human missions to the Moon and Mars. Powerful laboratory instruments, such as flow cytometers, are generally too...
9.
Zheng M, Charvat J, Zwart S, Mehta S, Crucian B, Smith S, et al.
Front Physiol
. 2023 Jul;
14:1219221.
PMID: 37520819
From the early days of spaceflight to current missions, astronauts continue to be exposed to multiple hazards that affect human health, including low gravity, high radiation, isolation during long-duration missions,...
10.
Wiencek J, Das S, Beheshti A, Crucian B, Karouia F, Trudel G, et al.
Clin Chem
. 2023 Apr;
69(5):442-449.
PMID: 37038963
No abstract available.