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Brian D Nicholson

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Articles 115
Citations 1594
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Recent Articles
1.
Williamson E, Tazare J, Bhaskaran K, Walker A, McDonald H, Tomlinson L, et al.
Wellcome Open Res . 2025 Feb; 5:243. PMID: 39931522
On March 11th 2020, the World Health Organization characterised COVID-19 as a pandemic. Responses to containing the spread of the virus have relied heavily on policies involving restricting contact between...
2.
Black G, Nicholson B, Moreland J, Fulop N, Lyratzopoulos G, Baxter R
BMJ Qual Saf . 2025 Jan; PMID: 39880649
Background: Over the past two decades, the UK has actively developed policies to enhance early cancer diagnosis, particularly for individuals with non-specific cancer symptoms. Non-specific symptom (NSS) pathways were piloted...
3.
Beaton D, Sharp L, Trudgill N, Thoufeeq M, Nicholson B, Rogers P, et al.
Gastrointest Endosc . 2025 Jan; PMID: 39788213
Background And Aims: Analysis of national colonoscopy quality using automatically uploaded data from a national database, including exploring performance variation. Methods: Data on all colonoscopies performed in the UK 01/03/2019-29/02/2020...
4.
Vavoulis D, Cutts A, Thota N, Brown J, Sugar R, Rueda A, et al.
Nat Commun . 2025 Jan; 16(1):430. PMID: 39779727
The analysis of circulating tumour DNA (ctDNA) through minimally invasive liquid biopsies is promising for early multi-cancer detection and monitoring minimal residual disease. Most existing methods focus on targeted deep...
5.
Black G, Khalid A, Lyratzopoulos G, Duffy S, Nicholson B, Fulop N
J Health Serv Res Policy . 2024 Dec; 30(1):21-30. PMID: 39673231
Objectives: This study aimed to explore the policy implementation of non-specific symptom pathways within the English National Health Service. Methods: A multi-site ethnographic project was conducted in four hospitals that...
6.
White B, Zakkak N, Renzi C, Rafiq M, Gonzalez-Izquierdo A, Denaxas S, et al.
Br J Gen Pract . 2024 Dec; PMID: 39658074
Background: Presenting to primary care with fatigue is associated with a wide range of conditions, including cancer, although their relative likelihood is unknown. Aim: To quantify associations between new-onset fatigue...
7.
Nicholson B, Virdee P, Aveyard P, Price S, Hobbs F, Koshiaris C, et al.
BMJ . 2024 Oct; 387:e080199. PMID: 39414353
Objective: To quantify the predictive value of unexpected weight loss for cancer according to patient's age, sex, smoking status, and concurrent clinical features (symptoms, signs, and abnormal blood test results)....
8.
Briones J, Diaz P, Nicholson B
Front Oncol . 2024 Oct; 14:1437574. PMID: 39411122
Background: The role of high-dose chemotherapy followed by autologous hematopoietic cell transplantation in the management of patients with relapsed/refractory germ-cell tumors has not been established in prospective studies. Our aim...
9.
Jackson A, Virdee P, Tonner S, Oke J, Perera R, Riahi K, et al.
Lancet Oncol . 2024 Oct; 25(11):1476-1486. PMID: 39395435
Background: Cancer places a high burden on society and health-care systems. Cancer research requires high-quality data, which is resource-intensive to obtain. Using administrative datasets such as cancer registries could improve...
10.
Heath L, Stevens R, Nicholson B, Wherton J, Gao M, Callan C, et al.
BMC Med . 2024 Sep; 22(1):412. PMID: 39334345
Background: Action on smoking, obesity, excess alcohol, and physical inactivity in primary care is effective and cost-effective, but implementation is low. The aim was to examine the effectiveness of strategies...