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Brian D Melanson

Explore the profile of Brian D Melanson including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Melanson B, Cabrita M, Bose R, Hamill J, Pan E, Brochu C, et al.
Nucleic Acids Res . 2013 Apr; 41(11):5692-703. PMID: 23605047
The DNA damage-binding protein 2 (DDB2) is an adapter protein that can direct a modular Cul4-DDB1-RING E3 Ligase complex to sites of ultraviolet light-induced DNA damage to ubiquitinate substrates during...
2.
Brochu C, Cabrita M, Melanson B, Hamill J, Lau R, Pratt M, et al.
PLoS One . 2013 Feb; 8(2):e57426. PMID: 23437386
The cold inducible RNA binding protein (CIRBP) responds to a wide array of cellular stresses, including short wavelength ultraviolet light (UVC), at the transcriptional and post-translational level. CIRBP can bind...
3.
Melanson B, Bose R, Hamill J, Marcellus K, Pan E, McKay B
RNA . 2011 Oct; 17(12):2222-34. PMID: 22020975
The p53 tumor suppressor is a DNA-damage-responsive sequence-specific transcriptional activator. The sustained activation of the p53 response is incompatible with cell growth and viability. To circumvent this issue, a variety...