Brian D Ackley
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Explore the profile of Brian D Ackley including associated specialties, affiliations and a list of published articles.
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33
Citations
592
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Recent Articles
1.
Kywe C, Lundquist E, Ackley B, Lansdon P
G3 (Bethesda)
. 2024 Mar;
14(5).
PMID: 38478633
Innate immunity functions as a rapid defense against broad classes of pathogenic agents. While the mechanisms of innate immunity in response to antigen exposure are well-studied, how pathogen exposure activates...
2.
Devkota S, Zhou R, Nagarajan V, Maesako M, Do H, Noorani A, et al.
Cell Rep
. 2024 Feb;
43(2):113761.
PMID: 38349793
Mutations that cause familial Alzheimer's disease (FAD) are found in amyloid precursor protein (APP) and presenilin, the catalytic component of γ-secretase, that together produce amyloid β-peptide (Aβ). Nevertheless, whether Aβ...
3.
4.
Lialys L, Lialys J, Salandrino A, Ackley B, Fardad S
Sci Rep
. 2023 May;
13(1):8615.
PMID: 37244967
While optical tweezers (OT) are mostly used for confining smaller size particles, the counter-propagating (CP) dual-beam traps have been a versatile method for confining both small and larger size particles...
5.
Aquino Nunez W, Combs B, Gamblin T, Ackley B
Front Aging
. 2022 Sep;
3:928574.
PMID: 36062211
Aging is the primary risk factor for Alzheimer's disease (AD) and related disorders (ADRDs). Tau aggregation is a hallmark of AD and other tauopathies. Even in normal aging, tau aggregation...
6.
Kaulich E, Carroll T, Ackley B, Tang Y, Hardege I, Nehrke K, et al.
Elife
. 2022 Jun;
11.
PMID: 35666106
Biological clocks are fundamental to an organism's health, controlling periodicity of behaviour and metabolism. Here, we identify two acid-sensing ion channels, with very different proton sensing properties, and describe their...
7.
Lansdon P, Carlson M, Ackley B
BMC Genomics
. 2022 Mar;
23(1):229.
PMID: 35321659
The soil-dwelling nematode Caenorhabditis elegans serves as a model system to study innate immunity against microbial pathogens. C. elegans have been collected from around the world, where they, presumably, adapted...
8.
Do N, Ackley B, Lansdon P
Microbiol Resour Announc
. 2022 Mar;
11(4):e0123921.
PMID: 35286161
Staphylococcus epidermidis is a frequent cause of nosocomial infections occurring after the insertion of indwelling medical devices. Here, we report the 2.5-Mb draft genome of S. epidermidis strain EVL2000, which...
9.
Tucker D, Adams C, Prasad G, Ackley B
J Dev Biol
. 2022 Jan;
10(1).
PMID: 35076532
Neurons form elaborate networks by guiding axons and dendrites to appropriate destinations. Neurites require information about the relative body axes during the initial projection from the cell body, and failure...
10.
Yang Z, Mattingly B, Hall D, Ackley B, Buechner M
J Cell Biol
. 2020 Aug;
219(11).
PMID: 32860501
Single-celled tubules represent a complicated structure that forms during development, requiring extension of a narrow cytoplasm surrounding a lumen exerting osmotic pressure that can burst the luminal membrane. Genetic studies...