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Brian Buehler

Explore the profile of Brian Buehler including associated specialties, affiliations and a list of published articles. Areas
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Citations 62
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Recent Articles
1.
Solomon G, Linnemann R, Rich R, Streby A, Buehler B, Hunter E, et al.
Lancet Respir Med . 2024 Aug; 12(12):947-957. PMID: 39208836
Background: CFTR modulators are approved for approximately 90% of people with cystic fibrosis in the USA and provide substantial clinical benefit. N1303K (Asn1303Lys), one of the most common class 2...
2.
DiFiglia S, Georgiopoulos A, Portenoy R, Seng E, Berdella M, Friedman D, et al.
J Cyst Fibros . 2023 Nov; 23(4):804-810. PMID: 37951787
Background: Little is known about the burden of illness experienced by people with cystic fibrosis (pwCF) since the advent of CF transmembrane conductance regulator (CFTR) modulator therapies. Studies that characterize...
3.
Zhou Z, Ye T, DeCaro E, Buehler B, Stahl Z, Bonavita G, et al.
Am J Pathol . 2019 Oct; 190(1):82-92. PMID: 31610175
Aberrant liver sirtuin 1 (SIRT1), a mammalian NAD-dependent protein deacetylase, is implicated in the pathogenesis of alcoholic liver disease (ALD). However, the role of intestinal SIRT1 in ALD is presently...