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Brian Betts

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Articles 16
Citations 151
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Recent Articles
1.
Herr M, Balderman S, Wallace P, Zhang Y, Tario Jr J, Buxbaum N, et al.
Transplant Cell Ther . 2024 May; 30(8):808.e1-808.e13. PMID: 38801976
Haploidentical (Haplo) allogeneic HCTs (alloHCT) have been used more frequently over the last decade as survival is similar to HLA-matched related donor (MRD) alloHCTs. We aimed to identify donor and...
2.
Beckman J, DaSilva A, Aronovich E, Nguyen A, Nguyen J, Hargis G, et al.
J Thromb Haemost . 2023 Feb; 21(5):1366-1380. PMID: 36738826
Background: Vascular activation is characterized by increased proinflammatory, pro thrombotic, and proadhesive signaling. Several chronic and acute conditions, including Bcr-abl-negative myeloproliferative neoplasms (MPNs), graft-vs-host disease, and COVID-19 have been noted...
3.
Sumransub N, Cao Q, Juckett M, Betts B, Holtan S, Jurdi N, et al.
Transplant Cell Ther . 2023 Jan; 29(4):263.e1-263.e7. PMID: 36682471
Autologous hematopoietic stem cell transplantation (ASCT) improves survival for patients with chemotherapy-sensitive lymphoma. Validated scoring systems are used in the clinical setting to predict treatment toxicity and survival; however, complications...
4.
Perez L, Fernandez H, Kharfan-Dabaja M, Khimani F, Betts B, Mishra A, et al.
Blood Adv . 2021 Jul; 5(13):2740-2750. PMID: 34242388
Immunomodulatory properties of histone deacetylase inhibitors represent a reasonable approach for acute graft-versus-host disease (aGVHD) prevention. We report a phase 2 trial evaluating panobinostat (PANO) administered over 26 weeks, starting...
5.
Jurdi N, Fair C, Rogosheske J, Shanley R, Arora M, Bachanova V, et al.
Transplant Cell Ther . 2021 Apr; 27(2):179.e1-179.e4. PMID: 33830033
Regimen-related toxicities with high-dose therapy followed by hematopoietic cell rescue leads to considerable patient distress, morbidity, and high readmission rates. Palifermin is a recombinant keratinocyte growth factor that is Food...
6.
Obeid K, Grzywacz B, Ferrieri P, Arbefeville S, Slungaard A, Betts B
Transpl Infect Dis . 2021 Mar; 23(4):e13610. PMID: 33783930
In the United States, toxoplasmosis following allogeneic hematopoietic stem transplant (allo-HCT) is very rare with a rate only between 0.5% and 2%. The reported rates of hemophagocytic lymphohistiocytosis (HLH) following...
7.
Jurdi N, Rogosheske J, DeFor T, Bejanyan N, Arora M, Bachanova V, et al.
Transplant Cell Ther . 2020 Oct; 27(1):84.e1-84.e5. PMID: 33053448
The high incidence of human herpesvirus-6 (HHV-6) reactivation, potentially interfering with engraftment after umbilical cord blood (UCB) hematopoietic cell transplantation (HCT), remains a major challenge. To potentially address this problem,...
8.
Dimaggio E, Zhou J, Caddell R, Tombleson R, Perkins J, Anasetti C, et al.
Leuk Lymphoma . 2020 Mar; 61(7):1678-1687. PMID: 32133897
Optimal conditioning chemotherapy for patients with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) remains uncertain. Myeloablative regimens such as fludarabine/busulfan are favored over reduced-intensity fludarabine/melphalan (Flu/Mel); however, it is...
9.
Khimani F, McDonald G, Shulman H, Betts B, Locke F, Fernandez H, et al.
Bone Marrow Transplant . 2018 Jun; 54(1):85-89. PMID: 29895929
Sirolimus-based graft vs. host disease (GVHD) prophylaxis is associated with higher incidence of veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) after allogeneic hematopoietic cell transplantation (HCT). However, whether the clinical manifestations and...
10.
Perez L, Fernandez H, Horna P, Riches M, Locke F, Field T, et al.
Bone Marrow Transplant . 2018 Apr; 53(11):1434-1444. PMID: 29670210
Glucocorticoids for primary therapy of acute GVHD have limited responses. A phase I/II trial tested 4 weeks of deacetylase inhibitor panobinostat started within 48 h of glucocorticoids (1 mg/kg/day prednisone...