Brian A MacDonald
Overview
Explore the profile of Brian A MacDonald including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
270
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0
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Recent Articles
1.
LeBleu V, Dai J, Tsutakawa S, MacDonald B, Alge J, Sund M, et al.
Dev Dyn
. 2023 Apr;
252(7):1046-1060.
PMID: 37002899
Background: Type IV collagen is an abundant component of basement membranes in all multicellular species and is essential for the extracellular scaffold supporting tissue architecture and function. Lower organisms typically...
2.
MacDonald B, Chakravarthy K, Davidson B, Mullan B, Alluri R, Hakansson A, et al.
Anesthesiology
. 2015 Jun;
123(3):590-602.
PMID: 26120770
Background: To minimize the risk of pneumonia, many anesthesiologists delay anesthesia-requiring procedures when patients exhibit signs of viral upper respiratory tract infection. Postinfluenza secondary bacterial pneumonias (SBPs) are a major...
3.
OConnell J, Sugimoto H, Cooke V, MacDonald B, Mehta A, LeBleu V, et al.
Proc Natl Acad Sci U S A
. 2011 Sep;
108(38):16002-7.
PMID: 21911392
Increased numbers of S100A4(+) cells are associated with poor prognosis in patients who have cancer. Although the metastatic capabilities of S100A4(+) cancer cells have been examined, the functional role of...
4.
Charytan D, Helfand A, MacDonald B, Cinelli A, Kalluri R, Zeisberg E
PLoS One
. 2011 Sep;
6(8):e23718.
PMID: 21886815
Background: Soluble endoglin, a TGF-β receptor, plays a key role in cardiovascular physiology. Whether circulating concentrations of soluble endoglin are elevated in CKD or underlie the high risk of cardiovascular...
5.
Lucas M, MacDonald B, Wagner G, Joyce S, Rector K
ACS Appl Mater Interfaces
. 2010 Aug;
2(8):2198-205.
PMID: 20735091
Lignocellulosic biomass offers economic and environmental advantages over corn starch for biofuels production. However, its fractionation currently requires energy-intensive pretreatments, due to the lignin chemical resistance and complex cell wall...
6.
MacDonald B, Sund M, Grant M, Pfaff K, Holthaus K, Zon L, et al.
Blood
. 2005 Oct;
107(5):1908-15.
PMID: 16254142
Goodpasture syndrome is an autoimmune vascular disease associated with kidney and lung failure, with pathogenic circulating autoantibodies targeted to a set of discontinuous epitope sequences within the noncollagenous domain-1 (NC1)...
7.
Priddy T, MacDonald B, Heller W, Nadeau O, Trewhella J, Carlson G
Protein Sci
. 2005 Mar;
14(4):1039-48.
PMID: 15741333
Phosphorylase kinase (PhK), a 1.3-MDa (alphabetagammadelta)(4) hexadecameric complex, is a Ca(2+)-dependent regulatory enzyme in the cascade activation of glycogenolysis. PhK comprises two arched (alphabetagammadelta)(2) octameric lobes that are oriented back-to-back...
8.
Wall M, Francis S, Corbin J, Grimes K, Richie-Jannetta R, Kotera J, et al.
Proc Natl Acad Sci U S A
. 2003 Feb;
100(5):2380-5.
PMID: 12591946
Using small-angle x-ray scattering, we have observed the cGMP-induced elongation of an active, cGMP-dependent, monomeric deletion mutant of cGMP-dependent protein kinase (Delta(1-52)PKG-I beta). On saturation with cGMP, the radius of...