Brett McKinnon
Overview
Explore the profile of Brett McKinnon including associated specialties, affiliations and a list of published articles.
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Articles
39
Citations
602
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Recent Articles
1.
Ochoa S, Rasquel-Oliveira F, McKinnon B, Haro M, Subramaniam S, Yu P, et al.
bioRxiv
. 2024 Nov;
PMID: 39605445
Endometriosis is a common gynecologic condition that causes chronic life-altering symptoms including pain, infertility, and elevated cancer risk. There is an urgent need for new non-hormonal targeted therapeutics to treat...
2.
Tanaka K, Subramaniam S, Atluri S, Amoako A, Mortlock S, Montgomery G, et al.
Cannabis Cannabinoid Res
. 2024 Sep;
PMID: 39286880
Anandamide (AEA) and 2-arachidonoylglycerol are endogenous agonists of the cannabinoid receptors and regulate and control many cellular functions. Their activities are governed by enzymes and proteins that regulate their synthesis,...
3.
Marla S, Mortlock S, Yoon S, Crawford J, Andersen S, Mueller M, et al.
Cells
. 2023 Jul;
12(13).
PMID: 37443771
Identifying tissue-specific molecular signatures of active regulatory elements is critical to understanding gene regulatory mechanisms. In this study, transcription start sites (TSS) and enhancers were identified using Cap analysis of...
4.
Mortlock S, McKinnon B, Montgomery G
Front Reprod Health
. 2022 Oct;
3:795464.
PMID: 36304015
The endometrium is a complex and dynamic tissue essential for fertility and implicated in many reproductive disorders. The tissue consists of glandular epithelium and vascularised stroma and is unique because...
5.
Tanaka K, Gilroy D, Subramaniam S, Lakshmi P, Bhadravathi Lokeshappa M, Wallace L, et al.
BMJ Open
. 2022 Oct;
12(10):e064073.
PMID: 36241351
Introduction: Endometriosis is a common gynaecological disease associated with pelvic pain and subfertility. There are no non-invasive diagnostic tests, medical management requires suppression of oestrogens and surgical removal is associated...
6.
Armour M, Avery J, Leonardi M, Van Niekerk L, Druitt M, Parker M, et al.
Reprod Fertil
. 2022 Aug;
3(3):C29-C39.
PMID: 35928674
Abstract: Endometriosis is a common yet under-recognised chronic disease with one in nine (more than 830,000) women and those assigned female at birth diagnosed with endometriosis by the age of...
7.
Tanaka K, Amoako A, Mortlock S, Rogers P, Holdsworth-Carson S, Donoghue J, et al.
Sci Rep
. 2022 Jun;
12(1):9400.
PMID: 35672435
Endocannabinoids mediate cellular functions and their activity is controlled by a complex system of enzymes, membrane receptors and transport molecules. Endocannabinoids are present in endometrium, a cyclical regenerative tissue requiring...
8.
Filby C, Wyatt K, Mortlock S, Cousins F, McKinnon B, Tyson K, et al.
J Pers Med
. 2021 Dec;
11(12).
PMID: 34945786
Endometrial organoids (EMO) are an important tool for gynecological research but have been limited by generation from (1) invasively acquired tissues and thus advanced disease states and (2) from women...
9.
Ma L, Andrieu T, McKinnon B, Duempelmann L, Peng R, Wotzkow C, et al.
J Steroid Biochem Mol Biol
. 2021 Jun;
212:105943.
PMID: 34144151
Endometriosis is a common, estrogen-dependent disease, in which endometrial tissue grows in the peritoneal cavity. These lesions often express low levels of progesterone receptors (PR), which potentially play an important...
10.
Kocbek V, Imboden S, Nirgianakis K, Mueller M, McKinnon B
Heliyon
. 2021 Feb;
7(2):e06099.
PMID: 33615005
Ovarian cancer is the most lethal gynecological cancer. Numerous subtypes exist, each with distinct risk factors and prognosis. What underlies these subtypes and their progression is not clear, although inflammation...