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Brett Ley

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Articles 55
Citations 3208
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Recent Articles
1.
Zhang D, Adegunsoye A, Oldham J, Kozlitina J, Garcia N, Poonawalla M, et al.
Eur Respir J . 2023 Aug; 62(5). PMID: 37591536
Background: Studies suggest a harmful pharmacogenomic interaction exists between short leukocyte telomere length (LTL) and immunosuppressants in idiopathic pulmonary fibrosis (IPF). It remains unknown if a similar interaction exists in...
2.
Adegunsoye A, Newton C, Oldham J, Ley B, Lee C, Linderholm A, et al.
Nat Commun . 2023 Mar; 14(1):1489. PMID: 36932145
Pulmonary fibrosis (PF) is characterized by profound scarring and poor survival. We investigated the association of leukocyte telomere length (LTL) with chronological age and mortality across racially diverse PF cohorts....
3.
Raymond S, Baker S, Liu Y, Bustamante M, Ley B, Horzewski M, et al.
PLoS One . 2022 Mar; 17(3):e0266173. PMID: 35353851
Respiratory failure complicates most critically ill patients with COVID-19 and is characterized by heterogeneous pulmonary parenchymal involvement, profound hypoxemia and pulmonary vascular injury. The high incidence of COVID-19 related respiratory...
4.
Myers L, Mark D, Ley B, Guarnieri M, Hofmeister M, Paulson S, et al.
Crit Care Med . 2022 Feb; 50(7):e638-e642. PMID: 35120044
Objectives: The respiratory rate-oxygenation (ROX) index is a fraction of oxygen saturation, Fio2, and respiratory rate that has been validated to predict receipt of invasive mechanical ventilation in patients receiving...
5.
Liu S, Chung M, Ley B, French S, Elicker B, Fiorentino D, et al.
Thorax . 2021 Jul; 76(12):1186-1192. PMID: 34272332
Background: Peripheral blood leucocyte telomere length (PBL-TL) is associated with outcomes in patients with idiopathic pulmonary fibrosis. Whether PBL-TL is associated with progression of systemic sclerosis-associated interstitial lung disease (SSc-ILD)...
6.
Hariri L, Roden A, Chung J, Danoff S, Gomez Manjarres D, Hartwig M, et al.
Ann Am Thorac Soc . 2021 May; 18(10):1601-1609. PMID: 34004127
Diagnosis of interstitial lung disease (ILD) requires a multidisciplinary discussion approach that includes clinicians, radiologists, and pathologists. Surgical lung biopsy (SLB) is currently the recommended standard in obtaining pathologic specimens...
7.
Adegunsoye A, Morisset J, Newton C, Oldham J, Vittinghoff E, Linderholm A, et al.
Eur Respir J . 2020 Oct; 57(3). PMID: 33122338
No abstract available.
8.
Tomassetti S, Ravaglia C, Wells A, Cavazza A, Colby T, Rossi G, et al.
Lancet Respir Med . 2020 Aug; 8(8):786-794. PMID: 32763205
Background: Transbronchial lung cryobiopsy (TBLC) has been introduced recently in the diagnosis of interstitial lung diseases. We aimed to evaluate the prognostic significance of the distinction between idiopathic pulmonary fibrosis...
9.
Farrand E, Iribarren C, Vittinghoff E, Levine-Hall T, Ley B, Minowada G, et al.
Chest . 2020 Jul; 159(1):219-227. PMID: 32717266
Background: Idiopathic pulmonary fibrosis (IPF) is a rare, chronic lung disease associated with substantial symptom burden, morbidity, and cost. Delivery of high-quality effective care in IPF requires understanding health-care resource...
10.
Ley B, Liu S, Elicker B, Henry T, Vittinghoff E, Golden J, et al.
Eur Respir J . 2020 Apr; 56(2). PMID: 32341108
No abstract available.