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Brenda Kischkel

Explore the profile of Brenda Kischkel including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 120
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Recent Articles
1.
Vuscan P, Roring R, Kischkel B, Tintore M, Cune J, de Lecea C, et al.
Cytokine . 2025 Jan; 187:156871. PMID: 39889564
ABBi16 is a high-complexity blend of β-1,3/1,6-glucans from Saccharomyces cerevisiae with strong immunomodulatory activities, that have been recently shown to support anti-tumoral immune responses through the induction of trained immunity....
2.
Badii M, Nica V, Straton A, Kischkel B, Gaal O, Cabau G, et al.
Immunology . 2024 Oct; 174(1):100-112. PMID: 39354748
Type I interferons (IFN1s) mediate innate responses to microbial stimuli and regulate interleukin (IL)-1 and IL-1 receptor antagonist (Ra) production in human cells. This study explores interferon-stimulated gene (ISG) alterations...
3.
Taira C, Dos Santos Dias L, Lichtenberger S, Whitehead A, Kischkel B, Netea M, et al.
J Immunol . 2024 Aug; 213(6):843-852. PMID: 39109925
Candida spp. are the fourth leading cause of bloodstream infections in hospitalized patients and the most common cause of invasive fungal infection. No vaccine against Candida spp. or other fungal...
4.
Niessink T, Stassen R, Kischkel B, Vuscan P, Emans P, van den Akker G, et al.
Osteoarthritis Cartilage . 2024 May; 32(10):1261-1272. PMID: 38806070
Objective: We aimed to characterize calcium-containing crystals present in synovial fluid from patients with knee osteoarthritis (OA) using Raman spectroscopy, and specifically investigate the biological effects of calcite crystals. Design:...
5.
Vuscan P, Kischkel B, Joosten L, Netea M
Immunol Rev . 2024 Mar; 323(1):164-185. PMID: 38551324
Over the past decade, compelling evidence has unveiled previously overlooked adaptive characteristics of innate immune cells. Beyond their traditional role in providing short, non-specific protection against pathogens, innate immune cells...
6.
Vuscan P, Kischkel B, Hatzioannou A, Markaki E, Sarlea A, Tintore M, et al.
Front Immunol . 2024 Feb; 15:1323333. PMID: 38415247
cell wall component β-glucan has been extensively studied for its ability to induce epigenetic and functional reprogramming of innate immune cells, a process termed . We show that a high-complexity...
7.
Ea H, Kischkel B, Chirayath T, Kluck V, Aparicio C, Loeung H, et al.
Ann Rheum Dis . 2024 Feb; 83(7):945-956. PMID: 38373842
Introduction: Untreated gout is characterised by monosodium urate (MSU) crystal accumulation responsible for recurrent flares that are commonly separated by asymptomatic phases. Both phases are inflammatory conditions of variable intensity....
8.
Bombassaro A, Figueiredo J, Taborda C, Joosten L, A Vicente V, Queiroz-Telles F, et al.
Mycoses . 2024 Jan; 67(1). PMID: 38282360
Fungal skin infections are distributed worldwide and can be associated with economic and social traits. The immune response related to skin cells is complex and its understanding is essential to...
9.
Kischkel B, Dos Santos J, Lopes-Bezerra L, Taborda C, Joosten L
Microb Pathog . 2024 Jan; 188:106550. PMID: 38262494
Cytokines of the interleukin (IL)-1 superfamily including the different IL-36 isoforms, have been reported as mediators of acute and chronic inflammation in human skin diseases, such as psoriasis. Here, we...
10.
Liu R, Kluck V, Kischkel B, Tercan H, Netea M, Crisan T, et al.
Cytokine . 2024 Jan; 175:156502. PMID: 38237388
Background: Hyperuricemia has been shown to be an inducer of pro-inflammatory mediators by human primary monocytes. To study the deleterious effects of hyperuricemia, a reliable and stable in vitro model...